Absorption Rate Limit Considerations for Oral Phosphate Prodrugs
dc.contributor.author | Forsberg, Markus | en_US |
dc.contributor.author | Fleisher, David | en_US |
dc.contributor.author | Li, Lilian Y. | en_US |
dc.contributor.author | Heimbach, Tycho | en_US |
dc.contributor.author | Flynn, Gordon L. | en_US |
dc.contributor.author | Matsunaga, Yasushi | en_US |
dc.contributor.author | Oh, Doo-Man | en_US |
dc.contributor.author | Savolainen, Jouko | en_US |
dc.contributor.author | Leppänen, Jukka | en_US |
dc.date.accessioned | 2006-09-08T19:19:26Z | |
dc.date.available | 2006-09-08T19:19:26Z | |
dc.date.issued | 2003-06 | en_US |
dc.identifier.citation | Heimbach, Tycho; Oh, Doo-Man; Li, Lilian Y.; Forsberg, Markus; Savolainen, Jouko; Leppänen, Jukka; Matsunaga, Yasushi; Flynn, Gordon; Fleisher, David; (2003). "Absorption Rate Limit Considerations for Oral Phosphate Prodrugs." Pharmaceutical Research 20(6): 848-856. <http://hdl.handle.net/2027.42/41498> | en_US |
dc.identifier.issn | 0724-8741 | en_US |
dc.identifier.issn | 1573-904X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41498 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12817887&dopt=citation | en_US |
dc.description.abstract | Purpose . To evaluate the potential of phosphate ester prodrugs to significantly improve the absorptive flux of poorly soluble parent drugs. | en_US |
dc.format.extent | 191753 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Medical Law | en_US |
dc.subject.other | Phosphate Ester Prodrug | en_US |
dc.subject.other | Protein Effects | en_US |
dc.subject.other | Absorption | en_US |
dc.subject.other | Biomedical Engineering | en_US |
dc.subject.other | Caco-2 | en_US |
dc.subject.other | Permeability | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Pharmacology/Toxicology | en_US |
dc.subject.other | Pharmacy | en_US |
dc.title | Absorption Rate Limit Considerations for Oral Phosphate Prodrugs | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109 | en_US |
dc.contributor.affiliationother | Aventis Pharmaceuticals, 1041 Route 202-206 North, P.O. Box 6800, Bridgewater, New Jersey, 08807 | en_US |
dc.contributor.affiliationother | Department of Pharmaceutical Chemistry, University of Kuopio, P.O. Box 1627, FIN-70211, Kuopio, Finland | en_US |
dc.contributor.affiliationother | Pharmaceutical Research Laboratory, Taiho Pharmaceutical Co., Ltd., Kowauchi-cho, Tokushima, 771-01, Japan | en_US |
dc.contributor.affiliationother | Department of Pharmacology and Toxicology, University of Kuopio, P.O. Box 1627, FIN-70211, Kuopio, Finland | en_US |
dc.contributor.affiliationother | Department of Pharmaceutical Chemistry, University of Kuopio, P.O. Box 1627, FIN-70211, Kuopio, Finland | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 12817887 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41498/1/11095_2004_Article_465513.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1023/A:1023827017224 | en_US |
dc.identifier.source | Pharmaceutical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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