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Rheological Characterization of Topical Carbomer Gels Neutralized to Different pH
dc.contributor.authorAckermann, Chrisitaen_US
dc.contributor.authorIslam, Mohammad T.en_US
dc.contributor.authorRodríguez-Hornedo, Naíren_US
dc.contributor.authorCiotti, Susanen_US
dc.date.accessioned2006-09-08T19:19:53Z
dc.date.available2006-09-08T19:19:53Z
dc.date.issued2004-07en_US
dc.identifier.citationIslam, Mohammad T.; Rodríguez-Hornedo, Naír; Ciotti, Susan; Ackermann, Chrisita; (2004). "Rheological Characterization of Topical Carbomer Gels Neutralized to Different pH." Pharmaceutical Research 21(7): 1192-1199. <http://hdl.handle.net/2027.42/41505>en_US
dc.identifier.issn0724-8741en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41505
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15290859&dopt=citationen_US
dc.description.abstractPurpose . The primary objective of this study is to perform detailed and extensive rheological characterization of rheology of carbomer (Carbopol) microgels formulated using a solvent system typically used in topical gel formulations. Solvents like glycerin and propylene glycol can alter rheology and drug delivery characteristics of topical gels owing to their different viscosities and due to the change in solvent-polymer and solvent-solvent interactions.en_US
dc.format.extent129532 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherPharmacyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherThixotropyen_US
dc.subject.otherYield Stressen_US
dc.subject.otherPharmaceutical Gel Formulationen_US
dc.subject.otherRheologyen_US
dc.subject.otherViscoelasticityen_US
dc.subject.otherTopical Gelen_US
dc.subject.otherCarbopolen_US
dc.subject.otherMicrogelen_US
dc.subject.otherConstitutive Modelen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherMedical Lawen_US
dc.titleRheological Characterization of Topical Carbomer Gels Neutralized to Different pHen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University Michigan, Ann Arbor, Michigan, 48109, USAen_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University Michigan, Ann Arbor, Michigan, 48109, USAen_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University Michigan, Ann Arbor, Michigan, 48109, USAen_US
dc.contributor.affiliationotherPfizer, Inc., Ann Arbor, Michigan, 48105, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid15290859en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41505/1/11095_2004_Article_489401.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/B:PHAM.0000033006.11619.07en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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