View Item 

Show simple item record

Spatial determinants of specificity in insulin action
dc.contributor.authorCorley Mastick, Cynthiaen_US
dc.contributor.authorRibon, Vereden_US
dc.contributor.authorSaltiel, Alan R.en_US
dc.contributor.authorPrinten, John A.en_US
dc.date.accessioned2006-09-11T15:56:26Z
dc.date.available2006-09-11T15:56:26Z
dc.date.issued1998-05en_US
dc.identifier.citationCorley Mastick, Cynthia; Printen, John A.; Ribon, Vered; Saltiel, Alan R.; (1998). "Spatial determinants of specificity in insulin action." Molecular and Cellular Biochemistry 182 (1-2): 65-71. <http://hdl.handle.net/2027.42/45334>en_US
dc.identifier.issn1573-4919en_US
dc.identifier.issn0300-8177en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/45334
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9609115&dopt=citationen_US
dc.description.abstractInsulin is a potent stimulator of intermediary metabolism, however the basis for the remarkable specificity of insulin's stimulation of these pathways remains largely unknown. This review focuses on the role compartmentalization plays in insulin action, both in signal initiation and in signal reception. Two examples are discussed: (1) a novel signalling pathway leading to the phosphorylation of the caveolar coat protein caveolin, and (2) a recently identified scaffolding protein, PTG, involved directly in the regulation of enzymes controlling glycogen metabolism.en_US
dc.format.extent98384 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers; Springer Science+Business Mediaen_US
dc.subject.otherCaveolaeen_US
dc.subject.otherOncologyen_US
dc.subject.otherCardiologyen_US
dc.subject.otherLife Sciencesen_US
dc.subject.otherMedical Biochemistryen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherCaveolinen_US
dc.subject.otherGlycogenen_US
dc.subject.otherProtein Targeting to Glycogen (PTG)en_US
dc.subject.otherDARPP32en_US
dc.subject.otherType I Protein Serine/Threonine Phosphatase (PP1)en_US
dc.subject.otherProtein Phosphorylationen_US
dc.titleSpatial determinants of specificity in insulin actionen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Cell Biology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, MI, 48105, USA; Department of Physiology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USAen_US
dc.contributor.affiliationumDepartment of Cell Biology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, MI, 48105, USA; Department of Physiology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USAen_US
dc.contributor.affiliationumDepartment of Cell Biology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, MI, 48105, USA; Department of Physiology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USAen_US
dc.contributor.affiliationotherDepartment of Cell Biology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, MI, 48105, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid9609115en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/45334/1/11010_2004_Article_156837.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1006835430797en_US
dc.identifier.sourceMolecular and Cellular Biochemistryen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
11010_2004_Article_156837.pdf
Size:
96.07KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe its collections in a way that respects the people and communities who create, use, and are represented in them. We encourage you to Contact Us anonymously if you encounter harmful or problematic language in catalog records or finding aids. More information about our policies and practices is available at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.