Diffusion imaging for evaluation of tumor therapies in preclinical animal models
dc.contributor.author | McConville, P. J. | en_US |
dc.contributor.author | Rehemtulla, Alnawaz | en_US |
dc.contributor.author | Chenevert, Thomas L. | en_US |
dc.contributor.author | Moody, J. B. | en_US |
dc.contributor.author | Stojanovska, Jadranka | en_US |
dc.contributor.author | Hall, Daniel E. | en_US |
dc.contributor.author | Moffat, Bradford A. | en_US |
dc.contributor.author | Ross, Brian D. | en_US |
dc.date.accessioned | 2006-09-11T19:35:19Z | |
dc.date.available | 2006-09-11T19:35:19Z | |
dc.date.issued | 2004-12 | en_US |
dc.identifier.citation | Moffat, B. A.; Hall, D. E.; Stojanovska, J.; McConville, P. J.; Moody, J. B.; Chenevert, T. L.; Rehemtulla, A.; Ross, B. D.; (2004). "Diffusion imaging for evaluation of tumor therapies in preclinical animal models." Magnetic Resonance Materials in Physics, Biology and Medicine 17 (3-6): 249-259. <http://hdl.handle.net/2027.42/47951> | en_US |
dc.identifier.issn | 1352-8661 | en_US |
dc.identifier.issn | 0968-5243 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47951 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15580371&dopt=citation | en_US |
dc.description.abstract | The increasing development of novel targeted therapies for treating solid tumors has necessitated the development of technology to determine their efficacy in preclinical animal models. One such technology that can non-invasively quantify early changes in tumor cellularity as a result of an efficacious therapy is diffusion MRI. In this overview we present some theories as to the origin of diffusion changes as a result of tumor therapy, a robust methodology for acquisition of apparent diffusion coefficient maps and some applications of determining therapeutic efficacy in a variety therapeutic regimens and animal models. | en_US |
dc.format.extent | 697655 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag; ESMRMB | en_US |
dc.subject.other | Biomedical Engineering | en_US |
dc.subject.other | Computer Appl. in Life Sciences | en_US |
dc.subject.other | Solid State Physics and Spectroscopy | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Tumor | en_US |
dc.subject.other | MRI | en_US |
dc.subject.other | Therapeutic Efficacy | en_US |
dc.subject.other | Diffusion | en_US |
dc.subject.other | Imaging / Radiology | en_US |
dc.subject.other | Health Informatics & Health Administration | en_US |
dc.subject.other | ADC | en_US |
dc.subject.other | Physiological, Cellular and Medical Topics | en_US |
dc.subject.other | Apparent Diffusion Coefficient | en_US |
dc.subject.other | NMR | en_US |
dc.title | Diffusion imaging for evaluation of tumor therapies in preclinical animal models | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Physics | en_US |
dc.subject.hlbsecondlevel | Electrical Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Center for Molecular Imaging, Department of Radiology, , University of Michigan, Ann Arbor, 1150 W. Medical Center Drive, MSRB III Rm 9303, , Ann Arbor, MI, 48109-0503, USA | en_US |
dc.contributor.affiliationum | Center for Molecular Imaging, Department of Radiology, , University of Michigan, Ann Arbor, 1150 W. Medical Center Drive, MSRB III Rm 9303, , Ann Arbor, MI, 48109-0503, USA | en_US |
dc.contributor.affiliationum | Center for Molecular Imaging, Department of Radiology, , University of Michigan, Ann Arbor, 1150 W. Medical Center Drive, MSRB III Rm 9303, , Ann Arbor, MI, 48109-0503, USA | en_US |
dc.contributor.affiliationum | Center for Molecular Imaging, Department of Radiology, , University of Michigan, Ann Arbor, 1150 W. Medical Center Drive, MSRB III Rm 9303, , Ann Arbor, MI, 48109-0503, USA | en_US |
dc.contributor.affiliationum | Department of Radiation Oncology, , University of Michigan, Ann Arbor, 1150 W. Medical Center Drive, MSRB III Rm 9303, , Ann Arbor, MI, 48109-0503, USA | en_US |
dc.contributor.affiliationum | Center for Molecular Imaging, Department of Radiology, , University of Michigan, Ann Arbor, 1150 W. Medical Center Drive, MSRB III Rm 9303, , Ann Arbor, MI, 48109-0503, USA | en_US |
dc.contributor.affiliationother | Molecular Imaging Research, , 924 N. Main, Ann Arbor, MI, 48104, USA | en_US |
dc.contributor.affiliationother | Molecular Imaging Research, , 924 N. Main, Ann Arbor, MI, 48104, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 15580371 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47951/1/10334_2004_Article_79.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/s10334-004-0079-z | en_US |
dc.identifier.source | Magnetic Resonance Materials in Physics, Biology and Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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