Application of selective saturation to image the dynamics of arterial blood flow during brain activation using magnetic resonance imaging
dc.contributor.author | Vazquez, Alberto L. | en_US |
dc.contributor.author | Lee, Gregory R. | en_US |
dc.contributor.author | Hernandez-Garcia, Luis | en_US |
dc.contributor.author | Noll, Douglas C. | en_US |
dc.date.accessioned | 2007-01-17T15:54:29Z | |
dc.date.available | 2007-01-17T15:54:29Z | |
dc.date.issued | 2006 | en_US |
dc.identifier.citation | Vazquez, Alberto L.; Lee, Gregory R.; Hernandez-Garcia, Luis; Noll, Douglas C. (2006)."Application of selective saturation to image the dynamics of arterial blood flow during brain activation using magnetic resonance imaging." Magnetic Resonance in Medicine 9999(9999): NA-NA. <http://hdl.handle.net/2027.42/49296> | en_US |
dc.identifier.issn | 0740-3194 | en_US |
dc.identifier.issn | 1522-2594 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/49296 | |
dc.description.abstract | A saturation-based approach is proposed to image the arterial blood flow signal with temporal resolution of 1 to 2 s and in-plane spatial resolution of a few millimeters. Using a saturation approach to suppress the undesired background stationary signal allows the blood water that enters the slice to be imaged at some specified later time. Since the blood protons that are being imaged are not restricted to the intravascular space, this technique is also sensitive to tissue perfusion signal contributions. The signal uptake characteristics of the saturation method proposed were used to study the different signal contributions as a function of the acquisition parameters. A typical perfusion acquisition (FAIR) was also used for comparison. The proposed method was demonstrated in a functional motor activation experiment and the observed signal changes were smaller than those obtained using the FAIR acquisition. The dynamics of the saturation method and FAIR temporal signal changes were investigated and time constants between 2 and 44 s were estimated. The tissue signal contribution to the saturation method's signal was small over the range of acquisition parameters that sensitized it to the arterial compartment. Magn Reson Med, 2006. © 2006 Wiley-Liss, Inc. | en_US |
dc.format.extent | 862382 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Imaging | en_US |
dc.title | Application of selective saturation to image the dynamics of arterial blood flow during brain activation using magnetic resonance imaging | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Functional MRI Laboratory, University of Michigan, Ann Arbor, Michigan, USA ; 2360 Bonisteel Boulevard, BIRB, Room 1073, Functional MRI Laboratory, University of Michigan, Ann Arbor, MI 48109-2108, USA | en_US |
dc.contributor.affiliationum | Functional MRI Laboratory, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Functional MRI Laboratory, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Functional MRI Laboratory, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/49296/1/1181_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/mrm.20813 | en_US |
dc.identifier.source | Magnetic Resonance in Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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