Now showing items 1-10 of 94
A radiation hybrid map of the proximal short arm of the human X chromosome spanning incontinentia pigmenti 1 (IP1) translocation breakpoints
(Elsevier, 1992-11)
Radiation hybrid mapping was used in combination with physical mapping techniques to order and estimate distances between 14 loci in the proximal region of the short arm of the human X chromosome. A panel of radiation ...
Neurotoxic esterase: Characterization of the solubilized enzyme and the conditions for its solubilization from chicken brain microsomal membranes with ionic, zwitterionic, or nonionic detergents
(Elsevier, 1987-05-01)
Neurotoxic esterase (NTE) is a membrane-bound protein found in highest concentration in brain and lymphocytes. The enzyme has no known physiological function, but its organophosphorylation and aging in neural tissue are ...
Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07)
The ratio of male and female genetic map distances varies dramatically across the human genome. Despite these sex differences in genetic map distances, most multipoint linkage analyses use sex-averaged genetic maps. We ...
Composition and origin of summertime air pollutants at Deep Creek Lake, Maryland
(Elsevier, 1989)
A 1 month intensive summertime field study conducted in rural western Maryland resulted in a comprehensive set of fine particle, gaseous and meteorological data. Sulfur in the assumed form of ammonium sulfate accounted for ...
Non-parametric estimation of gap time survival functions for ordered multivariate failure time data
(John Wiley & Sons, Ltd., 2004-06-30)
Times between sequentially ordered events (gap times) are often of interest in biomedical studies. For example, in a cancer study, the gap times from incidence-to-remission and remission-to-recurrence may be examined. Such ...
A shared random effects model for censored medical costs and mortality
(John Wiley & Sons, Ltd., 2006)
In this paper, we propose a model for medical costs recorded at regular time intervals, e.g. every month, as repeated measures in the presence of a terminating event, such as death. Prior models have related monthly medical ...
Semiparametric inferences for association with semi-competing risks data
(John Wiley & Sons, Ltd., 2005)
In many biomedical studies, it is of interest to assess dependence between bivariate failure time data. We focus here on a special type of such data, referred to as semi-competing risks data. In this article, we develop ...
Follicle-stimulating hormone signal transduction: Role of carbohydrate in aromatase induction in immature rat Sertoli cells
(Elsevier, 1991-08)
Receptor activated adenylate cyclase acts as a major transmembrane signalling system. It is widely accepted that upon binding to its receptor, follicle-stimulating hormone (FSH) activates the cAMP-dependent pathway which ...
Syndrome X: Is it for real?
(Wiley Subscription Services, Inc., A Wiley Company, 1998)
The term syndrome X has been applied to the association of hypertension, non-insulin-dependent diabetes mellitus (NIDDM), android obesity, insulin resistance, and dyslipidemia. In this paper, based on population samples ...