Now showing items 11-20 of 47
Localization of the human homolog of the yeast cell division control 27 gene (CDC27) proximal to ITGB3 on human chromosome 17q21.3
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-09)
The human homolog of the Saccharomyces cerevisiae cell division control 27 gene (CDC27) was mapped to human chromosome 17q12-q21 using a panel of human/rodent somatic cell hybrids and localized distal to the breast cancer ...
Detection of oxidative mutagens in an urban air-particulate extract: a preliminary study
(Elsevier, 1992-12)
The Ames assays strains TA98 and TA100 have been useful in characterizing complex mixtures from organic solvent extracts of particles from diesel-powered vehicles, ambient air, and other sources. In this paper we report ...
Chronic ethanol consumption depresses hypothalamic-pituitary-adrenal function in aged rats
(Elsevier, 1991)
In separate experiments, nine (n=20) and fifteen (n=12) month old rats were treated with either 6% ethanol or 12% sucrose (to balance caloric intake) in the drinking water to examine the effect of chronic ethanol consumption ...
Lod scores for gene mapping in the presence of marker map uncertainty
(John Wiley & Sons, Inc., 2001-07)
Multipoint lod scores are typically calculated for a grid of locus positions, moving the putative disease locus across a fixed map of genetic markers. Changing the order of a set of markers and/or the distances between the ...
Assessment of sex-specific genetic and environmental effects on bone mineral density
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09)
Although it is widely accepted that genes contribute significantly to the variation in bone mineral density (BMD), the nature of the genetic contribution is poorly defined. There are large gender differences in BMD, although ...
L-threonine dehydrogenase of Escherichia coli K-12
(Elsevier, 1978-11-14)
SummaryA rapid method for purifying L-threonine dehydrogenase from Escherichia coli K-12 cells, grown on a medium containing L-threonine as carbon source, has been developed. The procedure consists of three fractionation ...
An evaluation of the replicate pool method: quick estimation of genome-wide linkage peak p -values
(Wiley Subscription Services, Inc., A Wiley Company, 2006-05)
The calculation of empirical p -values for genome-wide non-parametric linkage tests continues to present significant computational challenges for many complex disease mapping studies. The gold standard approach is to use ...
Synergism of mutant frequencies in the mouse lymphoma cell mutagenicity assay by binary mixtures of methyl methanesulfonate and ethyl methanesulfonate
(Elsevier, 1988-10)
The effect of mixed mutagen exposures on the rate and type of induced mutants was studied in the L5178Y/TK+/- --> TK-/- mouse lymphoma cell mutagenicity assay. In this assay, exposure to ethyl methanesulfonate (EMS) ...
Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns
(Springer-Verlag, 2005-11)
Mitochondria play an integral role in ATP production in cells and are involved in glucose metabolism and insulin secretion, suggesting that variants in the mitochondrial genome may contribute to diabetes susceptibility. ...
Strain-specific modification of lethality in fucose-deficient mice
(Springer-Verlag; Springer-Verlag New York Inc., 2003-02)
Abstract