View Item 

Show simple item record

Synthesis and Erosion Properties of PEG-Containing Polyanhydrides
dc.contributor.authorHou, Sijianen_US
dc.contributor.authorMcCauley, Laurie K.en_US
dc.contributor.authorMa, Peter X.en_US
dc.date.accessioned2007-09-20T18:55:30Z
dc.date.available2008-09-08T14:25:12Zen_US
dc.date.issued2007-05-10en_US
dc.identifier.citationHou, Sijian; McCauley, Laurie K.; Ma, Peter X. (2007)."Synthesis and Erosion Properties of PEG-Containing Polyanhydrides." Macromolecular Bioscience 7(5): 620-628. <http://hdl.handle.net/2027.42/56103>en_US
dc.identifier.issn1616-5187en_US
dc.identifier.issn1616-5195en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/56103
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=17457940&dopt=citationen_US
dc.description.abstractTo tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis( p -carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with increasing PEG content. Correspondingly, the erosion rate increases with increasing PEG content, whereas it decreases with increasing specimen thickness. This indicates that the incorporation of poly(ethylene glycol) into traditional two-component polyanhydrides retains their surface erosion properties while making the erosion rate tunable. The new polyanhydrides hold potential for drug delivery applications.en_US
dc.format.extent345740 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWILEY-VCH Verlagen_US
dc.subject.otherChemistryen_US
dc.subject.otherBiochemistry and Biotechnologyen_US
dc.titleSynthesis and Erosion Properties of PEG-Containing Polyanhydridesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Periodontics and Oral Medicine, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USA ; Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA ; Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USA. Fax: +1 734 647 2110en_US
dc.identifier.pmid17457940en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/56103/1/620_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/mabi.200600256en_US
dc.identifier.sourceMacromolecular Bioscienceen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
620_ftp.pdf
Size:
337.6KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe its collections in a way that respects the people and communities who create, use, and are represented in them. We encourage you to Contact Us anonymously if you encounter harmful or problematic language in catalog records or finding aids. More information about our policies and practices is available at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.