In vitro antimicrobial and in vivo antioomycete activities of the novel antibiotic thiobutacin
dc.contributor.author | Lee, Jung Yeop | en_US |
dc.contributor.author | Sherman, David H. | en_US |
dc.contributor.author | Hwang, Byung Kook | en_US |
dc.date.accessioned | 2008-02-04T19:21:24Z | |
dc.date.available | 2009-02-03T16:28:49Z | en_US |
dc.date.issued | 2008-02 | en_US |
dc.identifier.citation | Lee, Jung Yeop; Sherman, David H; Hwang, Byung Kook (2008). " In vitro antimicrobial and in vivo antioomycete activities of the novel antibiotic thiobutacin." Pest Management Science 64(2): 172-177. <http://hdl.handle.net/2027.42/57925> | en_US |
dc.identifier.issn | 1526-498X | en_US |
dc.identifier.issn | 1526-4998 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/57925 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18069650&dopt=citation | en_US |
dc.description.abstract | BACKGROUND: A number of synthetic fungicides are not effective when confronted by oomycete pathogens because many fungicide targets are absent from oomycetes. Moreover, resistance to fungicides has already arisen in oomycete species, and thus development of new, effective and safe compounds for use in oomycete disease control is necessary. RESULTS: Zoospore lysis began at 10 µg mL −1 of thiobutacin, and most of the zoospores were collapsed at 50 µg mL −1 . Thiobutacin also revealed inhibitory activity against the cyst germination and hyphal growth of Phytophthora capsici at 50 µg mL −1 . Treatment with thiobutacin exhibited protective activity against development of Phytophthora disease on pepper plants. CONCLUSION: The authors verified in vitro antioomycete activity of thiobutacin against P. capsici and its control efficacy against Phytophthora blight in vivo . This is the first report to demonstrate in vivo antioomycete activity of the novel antibiotic thiobutacin against P. capsici infection. Copyright © 2007 Society of Chemical Industry | en_US |
dc.format.extent | 149877 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | John Wiley & Sons, Ltd. | en_US |
dc.subject.other | Chemistry | en_US |
dc.subject.other | Food Science, Agricultural, Medicinal and Pharmaceutical Chemistry | en_US |
dc.title | In vitro antimicrobial and in vivo antioomycete activities of the novel antibiotic thiobutacin | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Korea ; Life Sciences Institute and Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Life Sciences Institute and Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationother | Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Korea ; Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Korea | en_US |
dc.identifier.pmid | 18069650 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/57925/1/1494_ftp.pdf | |
dc.identifier.doi | http://dx.doi.org/10.1002/ps.1494 | en_US |
dc.identifier.source | Pest Management Science | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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