Now showing items 1-10 of 34
The effects of footshock stress on regional brain dopamine metabolism and pituitary [beta]-endorphin release in rats previously sensitized to amphetamine
(Elsevier, 1987-07)
The repeated intermittent administration of amphetamine (AMP) produces an enduring enhancement in the response of dopamine (DA) systems in the brain to a subsequent "challenge" with amphetamine. However, former amphetamine ...
Immunocytochemical localization of pro-opiomelanocortin-derived peptides in the adult rat spinal cord
(Elsevier, 1986-07-16)
A dispersed descending pro-opiomelanocortin (POMC) fiber system has been demonstrated by peroxidase-antiperoxidase (PAP) immunocytochemistry in the adult rat spinal cord. [beta]-endorphin, adrenocorticotrophic hormone ...
Enkephalinase: Selective inhibitors and partial characterization
(Elsevier, 1980)
There are at least two types of enzymes in brain, endopeptidases and aminopeptidases, which metabolize enkephalins. Evidence is presented to suggest that enkephalinase, an endopeptidase cleaving at the Gly-Phe bond, is ...
A sensitive coupled HPLC/RIA technique for separation of endorphins: Multiple forms of B-endorphin in rat pituitary intermediate vs. anterior lobe
(Elsevier, 1981-08)
A technique is described which couples High Performance Liquid Chromatography (HPLC) to radioimmuno assays (RIA), thus achieving high sensitivity with good specificity. This method allows the separation and detection of ...
Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain
(Elsevier, 1984-12)
The immunocytochemical distribution of Proopiomelanocortin (POMC) peptides ([beta]-endorphin, ACTH, [alpha]-MSH, 16K fragment) was studied in the brain of the rhesus monkey (Macaca mulatta). Some animals were administered ...
Strategies for studying opioid peptide regulation at the gene, message and protein levels
(Elsevier, 1984)
Three opioid peptide precursors have been isolated and characterized in endocrine and nervous tissue: pro-opiomelanocortin, pro-enkephalin, and pro-dynorphin. Since each of those opioid peptide systems have been extensively ...
Β-Endorphin/ACTH immunocytochemistry in the CNS of the lizard Anolis carolinensis : Evidence for a major mesencephalic cell group
(Wiley Subscription Services, Inc., A Wiley Company, 1984-11-10)
The immunocytochemical distribution of Β-endorphin and other proopiomelanocortin (POMC) peptides in the central nervous system of the lizard Anolis carolinensis was determined. Colchicine pretreatment was used to enhance ...
Anatomical relationship between opioid peptides and receptors in rhesus monkey brain
(Elsevier, 1984-12)
To determine whether opioid peptide-receptor pharmacological associations found in vitro (e.g., enkephalin-[delta], dynorphin-[kappa]) predict anatomical relationships in situ, immunocytochemical and receptor autoradiographic ...
Anatomy of CNS opioid receptors
(Elsevier, 1988)
There is a wide body of evidence to suggest the existence of at least three distinct opioid receptor types in the CNS, referred to as [mu], [delta], and [kappa]. This paper reviews some of the findings that have led to ...
The preferential release of beta-endorphin from the anterior pituitary lobe by Corticotropin Releasing Factor (CRF)
(Elsevier, 1986)
Although a number of investigators have shown that release of ACTH is accompanied by the release of Beta-endorphin ([beta]-End) and Beta-lipotropin ([beta]-LPH), the proportion of the latter two peptides released with ...