Now showing items 11-15 of 15
Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms : Cleavage at a single arginine residue
(Elsevier, 1994-01-03)
Processing of rat prodynorphin (proDyn) by the mouse prohormone convertase PCI was investigated. Recombinant vaccinia virus vectors were used to coexpress proDyn and PC1 in rat PC12 pheochromocytoma and mouse AtT-20 ...
Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects
(Elsevier, 2006-04-07)
Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect on the actions of dynorphin in these systems and dynorphin ...
Plasma measures of B-endorphin-like immunoreactivity in depressives and other psychiatric subjects
(Elsevier, 2006-04-07)
We report the utilization of a very sensitive radioimmunoassay for plasma B-END, which has enabled us to examine the suppressibility of B-END-like material, under dexamethasone challenge, on a population of depressed ...
The signal peptide of pro-opiomelancortin: Validation of a specific radioimmunoassay
(Elsevier, 2006-04-07)
The N-terminus portion of the POMC leader sequence (signal peptide) was synthesized, and an antiserum was raised against it. A radioimmunoassay was developed which is effective at a dilution of 1:500,000, and sensitive at ...
POMC in rhesus anterior pituitary and plasma: Evidence of N-acetylated [beta]-endorphin and [alpha]-MSH
(Elsevier, 1983)
Pro-opiomelanocortin (POMC) related peptides have been studied in rat tissue and plasma, but they have not been well characterized in the rhesus monkey. Since monkey pituitary may be more similar to the human pituitary ...