Now showing items 11-20 of 39
Inhibition of opiate tolerance by non-competitive receptor antagonists
(Elsevier, 1994-01-07)
Our laboratory and others have previously reported that the non-competitive (NMDA) receptor antagonist, MK-801, interferes with the development of tolerance to the analgesic effects of morphine. The present studies were ...
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques
(Elsevier, 1992-02)
D1, a subtype of the dopamine receptors, is widely distributed in the nervous system and has been shown to be positively coupled to adenylate cyclase. Using a combination of in vitro receptor autoradiographic and in situ ...
Some of the [alpha]-NH2-acetylated [beta]-endoprhin-like material in rat and monkey pituitary and brain is acetylated [alpha]- and [beta]-endorphin
(Elsevier, 1983)
There are several studies demonstrating the existence of [alpha]-NH2-acetylated (N-Ac) forms of [beta]-endorphin in the intermediate lobe of several species (1,4,6). These include N-Ac-[beta]-endorphin(1-31), N-Ac-[beta] ...
Paradoxical effect of corticosteroids on pituitary ACTH/[beta]-endorphin release in stressed animals
(Elsevier, 1988)
We have previously demonstrated a number of changes in the anterior lobe proopiomelanocortin (POMC) system in chronically stressed rats. The purpose of the present experiments was to investigate whether chronically stressed ...
Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin
(Elsevier, 2006-04-07)
The opioid peptide dynorphin has been described as widely distributed in CNS when measured by RIA. Our previous immunohistochemical studies have only demonstrated dynorphin cells as those containing AVP. We now report the ...
Colocalization of estrogen β-receptor messenger RNA with orphanin FQ, vasopressin and oxytocin in the rat hypothalamic paraventricular and supraoptic nuclei
(Springer-Verlag, 2003-05)
The functional significance of the novel estrogen receptor β in brain areas that exclusively contain the ERβ receptor subtype such as the paraventricular (PVN) and the supraoptic (SON) nuclei of the hypothalamus is not yet ...
Localization of neurons containing pro-opiomelanocortin-related peptides in the hypothalamus and midbrain of the lizard, Anolis carolinensis evidence for region-specific processing of [beta]-endorphin
(Elsevier, 1984-12-24)
Immunohistochemical analyses of the lizard brain, following colchicine pretreatment, revealed two populations of POMC-producing cell bodies located in medial-basal hypothalamus and the mesencephalic tegmentum. Analyses of ...
Pharmacological and anatomical evidence of selective [mu], [delta], and [chi] opioid receptor binding in rat brain
(Elsevier, 1986-12-03)
While the distribution of opioid receptors can be differentiated in the rat central nervous system, their precise localization has remained controversial, due, in part, to the previous lack of selective ligands and insensitive ...
Tritiated ethylketocyclazocine binding in rat brain: Differential distribution of binding sites across brain regions
(Elsevier, 1982-09)
In rat brain, 3H-EKC shows a relative regional distribution of binding which parallels that of 3H-morphine. Dynorphin(1-13) has a pattern similar to morphine and dissimilar to EKC in displacing the three labels. Dynorphin(1-13) ...
Characterization of the forms of [beta]-endorphin and [alpha]-MSH in the caudal medulla of the rat and guinea pig
(Elsevier, 1986-07-09)
The post-translational processing of pro-opiomelanocortin (POMC) in brain remains controversial. Classically, there was thought to be a single cell group in the arcuate nucleus with long projections through limbic structures. ...