Now showing items 21-30 of 49
Gamma-melanotropin response to ovine corticotropin releasing factor in normal humans
(Elsevier, 1987)
Plasma [gamma]-melanotropin was measured by a [gamma]3MSH-specific radioimmunoassay before and after a single bolus intravenous infusion of ovine corticotropin releasing factor (oCRF; 0.1 ug/kg) in seven normal men. A ...
Localization of neurons containing pro-opiomelanocortin-related peptides in the hypothalamus and midbrain of the lizard, Anolis carolinensis evidence for region-specific processing of [beta]-endorphin
(Elsevier, 1984-12-24)
Immunohistochemical analyses of the lizard brain, following colchicine pretreatment, revealed two populations of POMC-producing cell bodies located in medial-basal hypothalamus and the mesencephalic tegmentum. Analyses of ...
Pharmacological and anatomical evidence of selective [mu], [delta], and [chi] opioid receptor binding in rat brain
(Elsevier, 1986-12-03)
While the distribution of opioid receptors can be differentiated in the rat central nervous system, their precise localization has remained controversial, due, in part, to the previous lack of selective ligands and insensitive ...
Induction of analgesia by central administration of ORG 2766, an analog of ACTH4-9
(Elsevier, 1981-01-05)
Dose-dependent analgesia was produced by microinjection of ORG 2766 into the periaqueductal gray (PAG). This analgesia was found to be potent and long-lasting and occurred at doses which were equimolar to those necessary ...
Tritiated ethylketocyclazocine binding in rat brain: Differential distribution of binding sites across brain regions
(Elsevier, 1982-09)
In rat brain, 3H-EKC shows a relative regional distribution of binding which parallels that of 3H-morphine. Dynorphin(1-13) has a pattern similar to morphine and dissimilar to EKC in displacing the three labels. Dynorphin(1-13) ...
Characterization of the forms of [beta]-endorphin and [alpha]-MSH in the caudal medulla of the rat and guinea pig
(Elsevier, 1986-07-09)
The post-translational processing of pro-opiomelanocortin (POMC) in brain remains controversial. Classically, there was thought to be a single cell group in the arcuate nucleus with long projections through limbic structures. ...
Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat
(Elsevier, 1985-02)
The substantia nigra is among the richest pro-dynorphin terminal field regions in the rat brain. We therefore contrasted processing in this area to the known processing in the posterior pituitary. Fractionation of acid ...
[3H] dynorphin binding to guinea pig and rat brain
(Elsevier, 1983)
[3H] Dynorphin can be shown to bind to the brains of both rat and guinea pigs with approximately 50% specific binding. Characterization of the binding in terms of multiple opiate receptor types supports the kappa selectivity ...
Lateral hypothalamic innervation of the cerebral cortex: Immunoreactive staining for a peptide resembling but immunochemically distinct from pituitary/arcuate [alpha]-melanocyte stimulating hormone
(Elsevier, 1986-01)
The combination of retrograde transport of fluorescent dyes and indirect immunofluorescence has been used to study the putative neurotransmitter specificity of the tuberal lateral hypothalamic projection to the cerebral ...