Now showing items 21-30 of 69
Economics, Psychology, and Social Dynamics of Consumer Bidding in Auctions
(Kluwer Academic Publishers; Springer Science + Business Media, Inc., 2005-12)
With increasing numbers of consumers in auction marketplaces, we highlight some recent approaches that bring additional economic, social, and psychological factors to bear on existing economic theory to better understand ...
A framework to analyze multiple time series data: A case study with Streptomyces coelicolor
(Springer-Verlag; Society for Industrial Microbiology, 2006-02)
Transcriptional regulation in differentiating microorganisms is highly dynamic involving multiple and interwinding circuits consisted of many regulatory genes. Elucidation of these networks may provide the key to harness ...
Adenovirus binding to cultured synoviocytes triggers signaling through MAPK pathways and induces expression of cyclooxygenase-2
(John Wiley & Sons, Ltd., 2005-03)
Background Recombinant adenovirus can be administered in vivo to achieve transduction of a number of cell types including human synoviocytes. Immunogenicity of adenoviruses has limited their utility as vectors for gene ...
Recognizing protein folds by cluster distance geometry
(Wiley Subscription Services, Inc., A Wiley Company, 2005-07-01)
Cluster distance geometry is a recent generalization of distance geometry whereby protein structures can be described at even lower levels of detail than one point per residue. With improvements in the clustering technique, ...
Further development and validation of empirical scoring functions for structure-based binding affinity prediction
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-01)
New empirical scoring functions have been developed to estimate the binding affinity of a given protein-ligand complex with known three-dimensional structure. These scoring functions include terms accounting for van der ...
A Comparative Study of Human Muscle and Brain Creatine Kinases Expressed in Escherichia coli
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2000-01)
We report the expression of the human muscle (CK-MM) and brain (CK-BB) creatine kinases in Escherichia coli . The proteins have been purified to apparent homogeneity and several of their physical and kinetic properties ...
PEPT2-Mediated Uptake of Neuropeptides in Rat Choroid Plexus
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2001-06)
Purpose . The peptide transporter PEPT2 was recently shown to be functionally active in rat choroid plexus, suggesting that it may play a role in neuropeptide homeostasis in the cerebrospinal fluid. This study, therefore, ...
Binding MOAD (Mother Of All Databases)
(Wiley Subscription Services, Inc., A Wiley Company, 2005-08-15)
Binding MOAD (Mother of All Databases) is the largest collection of high-quality, protein–ligand complexes available from the Protein Data Bank. At this time, Binding MOAD contains 5331 protein–ligand complexes comprised ...
The Potential of Raman Spectroscopy as a Process Analytical Technique During Formulations of Topical Gels and Emulsions
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2004-10)
Purpose. The primary objective of this study is to investigate the possibility of using Raman spectroscopy as a process analytical technique (PAT) for quality control during manufacturing of topical dosage forms.
Amino Acid Ester Prodrugs of Floxuridine: Synthesis and Effects of Structure, Stereochemistry, and Site of Esterification on the Rate of Hydrolysis
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2003-09)
Purpose . To synthesize amino acid ester prodrugs of floxuridine (FUdR) and to investigate the effects of structure, stereochemistry, and site of esterification of promoiety on the rates of hydrolysis of these prodrugs in ...