Now showing items 41-50 of 69
Surface-modified poly(lactide- co -glycolide) nanospheres for targeted bone imaging with enhanced labeling and delivery of radioisotope
(Wiley Subscription Services, Inc., A Wiley Company, 2003-12-01)
Surface-modified nanospheres can be utilized for targeting drugs and diagnostic agents to the bone and bone marrow while extending their circulation time in the blood stream. The surface modification of poly(lactide- co ...
Restituting intestinal epithelial cells exhibit increased transducibility by adenoviral vectors
(John Wiley & Sons, Ltd., 2006-12)
Background and aims While mature enterocytes are resistant to transduction by adenovirus type 5 (Ad5) vectors, undifferentiated cells are transduced much more efficiently. Our purpose was to study enterocyte transduction ...
Toward Correct Protein Folding Potentials
(Kluwer Academic Publishers; Springer Science+Business Media, 2004-06)
Empirical protein folding potentialfunctions should have a global minimum nearthe native conformationof globular proteins that fold stably, andthey should give the correct free energy offolding. We demonstrate that otherwise ...
Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN)
(Springer-Verlag, 2004-04)
Lipids are an important component of total parenteral nutrition (TPN), contributing the largest caloric load per volume of solution and providing essential fatty acids necessary for survival. However, lipids are known to ...
Valganciclovir for cytomegalovirus prophylaxis in liver transplant recipients
(Wiley Subscription Services, Inc., A Wiley Company, 2006-06)
No abstract.
Efficacy and safety of low-dose valganciclovir in the prevention of cytomegalovirus disease in adult liver transplant recipients
(Wiley Subscription Services, Inc., A Wiley Company, 2006-01)
The efficacy and safety of valganciclovir (VGCV) for cytomegalovirus (CMV) prophylaxis in liver transplant recipients has not been established. We retrospectively compared the efficacy and safety of low-dose oral VGCV (450 ...
A GPIIb/IIIa bioreactor for specific treatment of immune thrombocytopenic purpura, an autoimmune disease. Preparation, in vitro characterization, and preliminary proof-of-concept animal studies
(Wiley Subscription Services, Inc., A Wiley Company, 2005-12-01)
Immune thrombocytopenic purpura (ITP) is an autoimmune disease that affects thousands of Americans each year. The resulting thrombocytopenia, which develops from destruction of platelets (PLT) by anti-PLT autoantibodies ...
Biowaiver monographs for immediate release solid oral dosage forms: Amitriptyline hydrochloride This paper reflects the scientific opinion of the authors and not the policies of regulating agencies.
(Wiley Subscription Services, Inc., A Wiley Company, 2006-05)
Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate release (IR) solid oral dosage forms containing amitriptyline hydrochloride are reviewed. ...
A Rational Approach to Personalized Anticancer Therapy: Chemoinformatic Analysis Reveals Mechanistic Gene-Drug Associations
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2003-06)
Purpose . To predict the response of cells to chemotherapeutic agents based on gene expression profiles, we performed a chemoinformatic study of a set of standard anticancer agents assayed for activity against a panel of ...
Goal hierarchies as antecedents of market structure
(Wiley Subscription Services, Inc., A Wiley Company, 2006-08)
Current models of market structure are descriptive in nature and lack theoretical grounding in consumer behavior. Such grounding is especially needed in the specification of marketing strategies. A self-regulatory model ...