Now showing items 1-1 of 1
Permeation of Buprenorphine and Its 3-Alkyl-Ester Prodrugs Through Human Skin
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1996-10)
Purpose . Homologous 3-alkyl-ester prodrugs (C 2 to C 4 ) of buprenorphine with decreased crystallinity have been synthesized and evaluated for transdermal delivery commensurate with opioid dependence treatment.