Now showing items 1-5 of 5
Model Features of a Cardiac lontophoretic Drug Delivery Implant
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-05)
Determination of water-soluble acid distribution in poly(lactide- co -glycolide)
(Wiley Subscription Services, Inc., A Wiley Company, 2004-02)
Determination of the kinetics of water-soluble degradation products inside poly(lactide- co -glycolide) (PLGA) delivery systems during polymer degradation is important to evaluate the polymer microclimate conditions, ...
Stabilization and Controlled Release of Bovine Serum Albumin Encapsulated in Poly(D, L-lactide) and Poly(ethylene glycol) Microsphere Blends
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2001-06)
Purpose . The acidic microclimate in poly(D, L-lactide-co-glycolide) 50/50 microspheres has been previously demonstrated by our group as the primary instability source of encapsulated bovine serum albumin (BSA). The ...
Stabilization of a model formalinized protein antigen encapsulated in poly(lactide- co -glycolide)-based microspheres
(John Wiley & Sons, Inc., 2001-10)
A formaldehyde-mediated aggregation pathway (FMAP) has been shown to be primarily responsible for the solid-state aggregation of lyophilized formalinized protein antigens [e.g., tetanus toxoid (TT) and formalinized bovine ...
BSA degradation under acidic conditions: A model for protein instability during release from PLGA delivery systems
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07)
Acidification of the internal poly(lactide- co -glycolide) (PLGA) microenvironment is considered one of the major protein stresses during controlled release from such delivery systems. A model protein, bovine serum albumin ...