Now showing items 1-7 of 7
A Solubility and Related Physicochemical Property Comparison of Buprenorphine and Its 3-Alkyl Esters
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-10)
Stereochemical course of the biosynthesis of 1-aminocyclopropane-1-carboxylic acid. I. Role of the asymmetric sulfonium pole and the [alpha]-amino acid center
(Elsevier, 1984-05-31)
The substrate stereospecificity of 1-aminocyclopropane-1-carboxylic acid synthase, a pyridoxal phosphate-containing enzyme, from the pericarp tissue of (tomatoes) was studied using the various stereoisomers of -adenosylmethionine ...
Alternate substrates and inhibitors of 1-aminocyclopropane-1-carboxylic acid synthase
(Elsevier, 1987-06)
Structural analogs of (-)-S-adenosyl--methionine (SAM), in which the heterocyclic base was modified, were used to initiate studies to elucidate the active site conformation of the enzyme 1-aminocyclopropane-1-carboxylic ...
Kinetic and Mutagenic Evidence for the Role of Histidine Residues in the Lycopersicon esculentum 1-Aminocyclopropane-1-carboxylic acid Oxidase
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1999-01)
The ACCO gene from Lycopersicon esculentum (tomato) has been cloned into the expression vector PT7-7. The highly expressed protein was recovered in the form of inclusion bodies. ACCO is inactivated by diethyl pyrocarbonate ...
Aquifex aeolicus 3-Deoxy- d - manno -2-Octulosonic Acid 8-Phosphate Synthase: A New Class of KDO 8-P Synthase?
(Springer-Verlag; Springer-Verlag New York Inc., 2001-02)
The relationship between 3-deoxy- d - manno 2-octulosonic acid 8-phosphate (KDO 8-P) synthase and 3-deoxy- d - arabino -2-heptulosonic acid 7-phosphate (DAH 7-P) synthase has not been adequately addressed in the literature. ...
Permeation of Buprenorphine and Its 3-Alkyl-Ester Prodrugs Through Human Skin
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1996-10)
Purpose . Homologous 3-alkyl-ester prodrugs (C 2 to C 4 ) of buprenorphine with decreased crystallinity have been synthesized and evaluated for transdermal delivery commensurate with opioid dependence treatment.