An image-based approach for designing and manufacturing craniofacial scaffolds
dc.contributor.author | Hollister, Scott J. | en_US |
dc.contributor.author | Levy, Richard A. | en_US |
dc.contributor.author | Chu, Tien-Min Gabriel | en_US |
dc.contributor.author | Halloran, John W. | en_US |
dc.contributor.author | Feinberg, Stephen E. | en_US |
dc.date.accessioned | 2010-06-01T21:02:54Z | |
dc.date.available | 2010-06-01T21:02:54Z | |
dc.date.issued | 2000-02 | en_US |
dc.identifier.citation | Hollister, Scott J . ; Levy, Richard A . ; Chu, Tien-Min; Halloran, John W . ; Feinberg, Stephen E . (2000). "An image-based approach for designing and manufacturing craniofacial scaffolds." International Journal of Oral & Maxillofacial Surgery 29(1): 67-71. <http://hdl.handle.net/2027.42/74139> | en_US |
dc.identifier.issn | 0901-5027 | en_US |
dc.identifier.issn | 1399-0020 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/74139 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=10691148&dopt=citation | en_US |
dc.description.abstract | Bone tissue engineering (BTE), which combines biomaterial scaffolds with biologically active factors, holds tremendous promise for reconstructing craniofacial defects. A significant challenge in craniofacial reconstructive BTE applications is the complex patient-specific geometry that must be reconstructed. In this paper, we present an image-based approach for designing and manufacturing patient-specific craniofacial biomaterial scaffolds directly from CT or MRI data. In this approach, voxel density distribution is used to define scaffold topology. The scaffold design topology is created using image processing techniques. This voxel density distribution is then converted to data that can be used to drive a Solid Free-Form Fabrication machine to either directly build the scaffold or build a mold for the scaffold. Several preliminary applications for craniofacial surgery, including a mandibular condyle scaffold, an orbital floor scaffold, and a general mandibular defect scaffold, are illustrated. Finally, we show applications to in vivo models. | en_US |
dc.format.extent | 205392 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Munksgaard International Publishers | en_US |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | Munksgaard 2000 | en_US |
dc.subject.other | Craniofacial Reconstruction | en_US |
dc.subject.other | Biomaterial Scaffolds | en_US |
dc.subject.other | Imaging | en_US |
dc.subject.other | Tissue Engineering | en_US |
dc.title | An image-based approach for designing and manufacturing craniofacial scaffolds | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Dentistry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Biomedical Engineering, Surgery (Orthopaedics) and Mechanical Engineering and Applied Mechanics, The University of Michigan; | en_US |
dc.contributor.affiliationum | Department of Materials Science and Engineering, The University of Michigan; | en_US |
dc.contributor.affiliationum | Department of Oral and Maxillofacial Surgery, The University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationother | Diagnostic Radiology Associates, Saginaw, MI; | en_US |
dc.identifier.pmid | 10691148 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/74139/1/j.1399-0020.2000.290115.x.pdf | |
dc.identifier.doi | 10.1034/j.1399-0020.2000.290115.x | en_US |
dc.identifier.source | International Journal of Oral & Maxillofacial Surgery | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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