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Specific Differences in the Inhibition Titers of the Anti-H Lectins from Cytisus sessilifolius and Ulex europaeus *

dc.contributor.authorPlato, Chris C.en_US
dc.contributor.authorGershowitz, Henryen_US
dc.date.accessioned2010-06-01T21:04:18Z
dc.date.available2010-06-01T21:04:18Z
dc.date.issued1961-05en_US
dc.identifier.citationPlato, Chris C.; Gershowitz, Henry (1961). "Specific Differences in the Inhibition Titers of the Anti-H Lectins from Cytisus sessilifolius and Ulex europaeus * ." Vox Sanguinis 6(3): 336-347. <http://hdl.handle.net/2027.42/74161>en_US
dc.identifier.issn0042-9007en_US
dc.identifier.issn1423-0410en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/74161
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=13736265&dopt=citationen_US
dc.description.abstractTest of two commonly used anti-H reagents (extracts from Cytisus sessilifolius and Ulex europaeus ) demonstrated that group O secretors have the highest titer of H substance, with A 2 , A 1 , B, and AB followhing in that order. A comparison between the two extracts indicated that saliva belonging to persons of group A 1 have about the same amount of both H u and H c (substances inhibiting the Ulex and Cytisus extracts respectively), A 2 and O groups have a much higher titer of H u substance than they do H c , and B and AB groups demonstrate exactly the opposite qualities, with higher H c than H u titers. The most plausible explanation of the data seems to be that at least two different types of anti-H specifities are involved (anti-H c and anti-H u ); these extracts, then, differ not only quantitatively, but qualitatively as well. RÉsumÉ Les test pratiquÉs avec deux rÉactifs anti-H utilisÉs habituellement (extraits du Cytisus sessilifolius et de l'Ulex europaeus) ont dÉmontrÉ que les secrÉteurs du groupe O possÈdent le plus de substances H et ensuite, par ordre dÉcroissant, les secrÉteurs des groupes A 2 , A 1 , B et AB. Une comparaison Établie entre les deux extraits a dÉmontrÉ que la salive des personnes de groupe A 1 a la mÊme quantitÉ de substances H c et H u (substances inhibant les extraits de Cytisus sessilifolius et d'Ulex europaeus respectivement), que la salive des personnes de groupe A 2 et O ont une contenance plus grande en substance H u , que la salive des personnes de groupe B et AB montre des propriÉtÉs exactement contraires avec une contenance plus forte en H c qu'en H u . L'explication la plus plausible de ces rÉsultats semble Être le fait qu'il y a au moins deux spÉcificitÉs diffÉrentes de l'anti-H (l'anti-H c et l'anti-H u ). Ces extraits se diffÉrencient non seulement au point de vue quantitatif mais Également au point de vue qualitatif. Zusammenfassung Untersuchungen mit zwei gebrÄuchlichen Anti-H-Reagentien (Extrakte von Cytisus sessilifolius und Ulex europaeus) zeigten, daß Sekretoren der Gruppe O die hÖchsten H-Substanz-Titer aufweisen. Bei Sekretoren der Gruppen A 2 , A 1 , B und AB sind die Titer niedriger, wobei der H-Substanz-Gehalt von den A 2 - zu den AB-Individuen progressiv abnimmt. Vergleichsuntersuchungen mit den beiden Extrakten zeigten, daß der Speichel von A 1 -Personen etwa gleicbviel H u - und H c -Substanz enthÄlt (H u hemmt Ulex; H c hemmt Cytisus). Der Speichel von A 2 und O-Sekretoren enthÄlt wesentlich mehr H u -als H c -Substanz. Der Speichel von B- und AB-Sekretoren enthÄlt umgekehrt mehr H c - als H u -Substanz. Die einfachste ErklÄrung dieser Befunde besteht in der Annhame, daß die Extrakte Anti-H-«AntikÖrper» mit unterschiedlicher SpezifitÄt enthalten. Die unter-schiedliche Wirkung der Extrakte beruht somit nicht bloß auf quantitativen, sondern auf qualitativen Differenzen der aktiven Komponenten.en_US
dc.format.extent514072 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1961 Blackwell Publishing Ltden_US
dc.titleSpecific Differences in the Inhibition Titers of the Anti-H Lectins from Cytisus sessilifolius and Ulex europaeus *en_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelOncology and Hematologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan Medical School, Department of Human Genetics Ann Arbor, Michiganen_US
dc.identifier.pmid13736265en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/74161/1/j.1423-0410.1961.tb03171.x.pdf
dc.identifier.doi10.1111/j.1423-0410.1961.tb03171.xen_US
dc.identifier.sourceVox Sanguinisen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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