Now showing items 1-9 of 9
More TORC for the gluconeogenic engine
(Wiley Subscription Services, Inc., A Wiley Company, 2006-03)
Hepatic gluconeogenesis plays a key role in the maintenance of glucose homeostasis. The hormone glucagon stimulates this process, whereas insulin and adiponectin are inhibitory. In a recent report, Koo et al identify the ...
Amylin increases cyclic AMP formation in L6 myocytes through calcitonin gene-related peptide receptors
(Elsevier, 1991-06-14)
The cellular function of amylin is investigated in L6 myocytes, a rat skeletal muscle cell line. Both rat amylin and human amylin-amide acutely cause a dose-dependent increase in cyclic AMP formation in L6 myocytes. 100 ...
The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen
(Elsevier, 1969-09-10)
The generation of O2-- in the reaction of reduced flavins and several flavoproteins has been shown. This has been demonstrated by the ability to catalyse the aerobic reduction of cytochrome and the inhibition of this ...
Nerve growth factor binds to the 140 kd trk proto-oncogene product and stimulates its association with the src homology domain of phospholipase C [gamma]1
(Elsevier, 1991-08-30)
The cellular actions of nerve growth factor (NGF) involve regulation of protein phosphorylation. In PC-12 pheochromocytoma cells, exposure of [125I]NGF followed by crosslinking indicates that the ligand binds to two discreet ...
Crystallization and preliminary X-ray diffraction studies of the cobalamin-binding domain of methionine synthase from Escherichia coli
(Elsevier, 1992-05-20)
Crystals of a cobalamin-binding domain (Mr = 28,000) have been grown in polyethylene glycol 6000 at pH 7.5, starting from solutions of intact (Mr = 133,000) cobalamin-dependent methionine synthase. The crystals are ...
Strain-specific modification of lethality in fucose-deficient mice
(Springer-Verlag; Springer-Verlag New York Inc., 2003-02)
Abstract
Conserved linkage of neurotrophin-3 and von Willebrand factor on mouse Chromosome 6
(Springer-Verlag; Springer-Verlag New York Inc., 1993-06)
Flavodoxin Is Required for the Activation of the Anaerobic Ribonucleotide Reductase
(Elsevier, 1993-12-15)
The inactive anaerobic ribonucleotide reductase from Escherichia coli is transformed by a multienzyme system and S-adenosylmethionine + NADPH into a radical protein that is enzymatically active. One of the activating enzyme ...
Spatial compartmentalization of signal transduction in insulin action
(John Wiley & Sons, Inc., 2001-03)
Insulin resistance is thought to be the primary defect in the pathophysiology of type 2 diabetes. Thus, understanding the cellular mechanisms of insulin action may contribute significantly to developing new treatments for ...