Now showing items 11-20 of 82
Neuroprotective effects of MK-801, TCP, PCP and CPP against induced neurotoxicity in an in vivo perinatal rat model
(Elsevier, 1989-06-19)
Three non-competitive antagonists (MK-801, TCP, PCP) and one competitive antagonist (CPP) of (NMDA) receptors, were compared for their ability to antagonize neurotoxic actions of NMDA injected into the brains of 7-day-old ...
Short-Term Adrenalectomy Increases Glucocorticoid and Mineralocorticoid Receptor mRNA in Selective Areas of the Developing Hippocampus
(Elsevier, 1993-10)
In the central nervous system, adrenal steroids bind to two different types of corticosteroid receptors: glucocorticoid (GR) or mineralocorticoid (MR). In vitro biochemical and autoradiographic techniques have been used ...
Predicted reciprocal serum creatinine at age 10 years as a measure of renal function in children with nephropathic cystinosis treated with oral cysteamine
(Springer-Verlag; IPNA, 1990-03)
The predicted reciprocal creatinine at age 10 years (PRC 10 ), a parameter of renal function based upon the linear relationship between reciprocal serum creatinine and age, incorporates age, serum creatinine, and rate of ...
Phosphoinositide metabolism and prostacyclin formation in retinal microvascular endothelium: Stimulation by adenine nucleotides
(Elsevier, 1990-01)
Phosphoinositide lipid metabolism and prostacyclin production are implicated in endothelium dependent vascular relaxation in large blood vessels. To determine if these biochemical pathways might be involved in the regulation ...
Gene expression of the insulin-like growth factors and their receptors in human neuroblastoma cell lines
(Elsevier, 1992-10)
Insulin-like growth factors (IGF) I and II are polypeptides with both growth-promoting and insulin-like metabolic effects. The developmentally specific expression of IGF I and II in the nervous system implies a role for ...
Transseptal left heart catheterization as an aid in the diagnosis of cor triatriatum
(Springer-Verlag, 1987-06)
A case of cor triatriatum is described in which transseptal left heart catheterization was useful in making the diagnosis by allowing easy access to the accessory chamber for pressure measurements and angiography.
Magnesium reduces (NMDA)-mediated brain injury in perinatal rats
(Elsevier, 1990-02-05)
We evaluated the neuroprotective effects of systemically administered magnesium against (NMDA)-mediated brain injury in perinatal rats. Postnatal day (PND) 7 rats received unilateral intrastriatal injections of 25 nmol ...
IGF receptor function and regulation in autocrine human neuroblastoma cell growth
(Elsevier, 1993-10-20)
Insulin-like growth factor-II (IGF-II) and its receptors (type I and II IGF receptors) are expressed in the nervous system in a tissue and developmentally specific manner. We have previously shown that SH-SY5Y human ...
Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia Presented in part at the 2005 American Society of Pediatric Hematology Oncology (ASPHO) Annual Meeting, May 14–17, 2005, Washington, DC.
(Wiley Subscription Services, Inc., A Wiley Company, 2006-09-15)
BACKGROUND. The purpose of the study was to determine the prevalence of metabolic syndrome, growth hormone deficiency, and cardiovascular risk factors among adult survivors of childhood acute lymphoblastic leukemia (ALL) ...
Glycine-extended post-translational processing intermediates of gastrin and cholecystokinin in the gut
(Elsevier, 1994-02-03)
Cholecystokinin (CCK) and gastrin are two polypeptide hormones of the gut that share complete structural homology in their carboxyl-terminal pentapeptide. Both peptides are biologically activated from their glycine-extended ...