Now showing items 21-30 of 82
The microsomal calcium-ATPase inhibitor thapsigargin is a neurotoxin in perinatal rodent brain
(Elsevier, 1992-10-12)
Thapsigargin is a potent inhibitor of the microsomal calcium-ATPase. We hypothesized that thapsigargin-induced liberation of calcium from sequestered intracellular sites could result in irreversible brain injury. To assess ...
Pressure-Regulated Volume Control vs Volume Control Ventilation in Infants After Surgery for Congenital Heart Disease
(Springer-Verlag; Springer-Verlag New York Inc., 2001-05)
The objective of this investigation was to compare how two modes of positive pressure ventilation affect cardiac output, airway pressures, oxygenation, and carbon dioxide removal in children with congenital heart disease ...
Positive-ion thermospray liquid chromatography--mass spectrometry: detection of organic acidurias
(Elsevier, 1990)
Positive-ion thermospray liquid chromatography--mass spectrometry (TSP-LC-MS) is used to detect organic acids via the direct injection of untreated urine from newborns and infants. Two methods are reported for the separation ...
Photodiode array ultraviolet spectrophotometric profiling of carboxylic acids in physiological fluids
(Elsevier, 1985)
In this paper the use of a computer-controlled photodiode array spectrophotometric detector for the high-performance liquid chromatographic (HPLC) profiling of carboxylic acids in physiological fluids is reported. The ...
NMDA, AMPA, and benzodiazepine binding site changes in Alzheimer's disease visual cortex
(Elsevier, 1993)
Quantitative receptor autoradiography was used to measure the laminar distribution of [3H]glycine and [3H]glutamate binding to the N-methyl-D-aspartate (NMDA) receptor complex, [3H]D,L-a-amino-3-hydroxy-5-methyl-4-isoxaz ...
MK-801 pretreatment enhances brain injury and increases brain recognition site binding in rats
(Elsevier, 1990)
Direct intracerebral administration of typically produces focal brain injury. (+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-immine maleate (MK-801), a non-competitive antagonist, can protect against -mediated ...
Protein microinjection by protease permeabilization of fibroblasts
(Elsevier, 1988-07)
Exposure of cultured diploid fibroblasts to protease solutions induces a hyperpermeable state which permits entry of exogenous macromolecules directly into the cytosol. We have exploited this finding to devise a microinjection ...
Current Status of Staged Reconstruction for Hypoplastic Left Heart Syndrome
(Springer-Verlag; Springer-Verlag New York Inc., 1998-07)
Once considered a uniformly fatal condition, the outlook for newborns with hypoplastic left heart syndrome has been dramatically altered with staged reconstructive procedures. Refinements in operative technique and ...
Radiography of thoracic intravascular stents in children with congenital heart disease
(Springer-Verlag, 1993-04)
Seventeen balloon expandable stents were placed in thoracic vessels in eleven children with vascular stenoses related to congenital heart lesions. We describe the normal radiographic appearance of three types of balloon ...
Adopting Immunization Recommendations: A New Dissemination Model
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1998-12)
Objective: This paper presents a new approach for understanding factors related to physician adoption of clinical guidelines, using children's vaccine recommendations as a case study. Methods: The model traces sequential ...