Now showing items 11-20 of 33
Prenatal Exposure of the Ovine Fetus to Androgens Sexually Differentiates the Steroid Feedback Mechanisms That Control Gonadotropin Releasing Hormone Secretion and Disrupts Ovarian Cycles
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2002-02)
Exposure of the female sheep fetus to exogenous testosterone in early pregnancy permanently masculinizes the reproductive neuroendocrine axis. Specifically, in utero androgens given to female lambs from day 30 to 90 of a ...
Expression of Corticotropin-Releasing Hormone Transgenes in Neurons of Adult and Developing Mice
(Elsevier, 1994-12)
The DNA sequences important for cell-specific expression and developmental regulation of corticotropin-releasing hormone (CRH) were analyzed in transgenic mice. A construct containing 0.5 kb of CRH 5' flanking DNA linked ...
Accumulated glutamate levels in the synaptic vesicle are not maintained in the absence of active transport
(Elsevier, 1990-03-14)
We have investigated factors which may affect accumulated glutamate levels in synaptic vesicles and glutamate efflux. Agents which dissipate the electrochemical proton gradient resulted in a rapid reduction of steady-state ...
Glutamate recognition sites in human fetal brain
(Elsevier, 1988-01-22)
We used in vitro autoradiography with [3H]glutamate to examine the distribution of glutamate recognition sites in 18 and 21 week gestation human fetal brains. We found a wide distribution of [3H]glutamate binding in both ...
A cellular wireless local area network with QoS guarantees for heterogeneous traffic
(Kluwer Academic Publishers; Springer Science+Business Media, 1998-03)
A wireless local area network (WLAN) or a cell with quality‐of‐service (QoS) guarantees for various types of traffic is considered. A centralized (i.e., star) network is adopted as the topology of a cell which consists of ...
Systemic administration of mk-801 protects against in perinatal rats
(Elsevier, 1990)
MK-801, a non-competitive antagonist of glutamate receptors, was tested for its ability to antagonize excitotoxic actions of or quisqualic acid injected into the brains of seven-day-old rats. Stereotaxic injection of ...
Psychosocial dwarfism: Detection, evaluation and management
(Elsevier, 1979)
Our experience with 35 children with psychosocial dwarfism (PSD) over five years Is reviewed. Diagnosis and management are difficult. A multidisciplinary approach to the evaluation allows for maximal observation of family ...
The glutamate analogue quisqualic acid is neurotoxic in striatum and hippocampus of immature rat brain
(Elsevier, 1986-10-30)
To assess the neurotoxic properties of the glutamate agonist quisqualic acid (QA) in immature brain, we injected this compound (100 nmol QA/l [mu]l) directly into the striatum of 7-day-old rats. QA produced neuronal necrosis ...
Interferon-Γ inhibits DNA synthesis and insulin-like growth factor-II expression in human neuroblastoma cells
(Wiley Subscription Services, Inc., A Wiley Company, 1993-04-01)
Interferon-Γ (IFN-Γ) is known to be an antiproliferative, differentiation agent in many cell types, including neuroblastoma. In this study, we determined the effects of IFN-Γ on cellular growth and expression of insulin-like ...