Now showing items 1-10 of 13
Evaluation of ( - )[18F]fluoroethoxybenzovesamicol as a new PET tracer of cholinergic neurons of the heart
(Elsevier, 1994-02)
18F-labeled ( - )fluoroethoxybenzovesamicol [( - )FEOBV] is a novel PET tracer which binds to the vesicular acetylcholine transporter of cholinergic neurons. To evaluate the in vivo binding specificity and kinetic properties ...
Characterization of [11C]tetrabenazine as an in vivo radioligand for the vesicular monoamine transporter
(Elsevier, 1994-02)
[11C]Tetrabenazine ([11C]TBZ) is a new in vivo radioligand for positron emission tomographic (PET) imaging of vesicular monoamine transporters. The in vivo distribution, metabolism and pharmacological specificity of [11C]TBZ ...
Scintigraphy of incidentally discovered bilateral adrenal masses
(Springer-Verlag, 1995-04)
The purpose of this study was to determine the patterns of iodine-131 6β-iodomethylnorcholesterol (NP-59) imaging and the correlation with computed tomography (CT)-guided adrenal biopsy and follow-up in patients with ...
Importance of intra-therapy single-photon emission tomographic imaging in calculating tumour dosimetry for a lymphoma patient
(Springer-Verlag, 1991-06)
The dosimetry for two, similarly sized tumours in a lymphoma patient being treated with non-bone marrow ablative, monoclonal antibody therapy is reported. The 45-year-old man was infused with 2.48 GBq (67 mCi) of 131 ...
Predictors of toxicity in treating patients with neuroblastoma by radiolabeled metaiodobenzylguanidine
(Springer-Verlag, 1994-01)
We searched for methods that would enable prescriptions of the maximum tolerable doses of iodine-131 metaiodobenzylguanidine (MIBG) and iodine-125 MIBG in the treatment of patients with neuroblastoma. We correlated doses, ...
Autoradiography-based, three-dimensional calculation of dose rate for murine, human-tumor xenografts
(Elsevier, 1993-11)
A Fast Fourier Transform method for calculating the three-dimensional dose rate distribution for murine, human-tumor xenografts is outlined. The required input includes evenly-spaced activity slices which span the tumor. ...
Synthesis of a nonpeptide carbon-11 labeled substance P antagonist for PET studies
(Elsevier, 1993-05)
CP 96,345 is a nonpeptide high affinity antagonist of the substance P (NK1) receptor. The radiosynthesis of [11C]CP 96,345 suitable for Positron Emission Tomography (PET) applications is described. [11C]CP 96,345 was ...
Synthesis of the 123I- and 125I-labeled cholinergic nerve marker (-)-5-iodobenzovesamicol
(Elsevier, 1993-11)
The highly toxic curaremimetic and cholinergic neuron marker (-)-5-iodobenzovesamicol (IBVM) has been labeled with iodine-125 and iodine-123. [125I]IBVM, suitable for animal distribution and ex vivo autoradiographic studies, ...
Phaeochromocytoma and functioning paraganglioma in childhood and adolescence: role of iodine 131 metaiodobenzylguanidine
(Springer-Verlag, 1991-03)
Phaeochromocytomas and functioning paragangliomas are rare tumours in childhood and adolescence. We review our experience of 43 cases (24 men, 19 women) who were first diagnosed at the age of ⩽ 18 years. All patients were ...