Now showing items 1-10 of 13
Cytogenetic analysis of posterior uveal melanoma
(Elsevier, 1993-03)
Cytogenetic analysis was performed on short-term cultures of primary tumor samples from seven patients with posterior uveal melanoma. Informative data were obtained from four patients, all of whom had a near-diploid ...
Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-15)
BACKGROUND A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal ...
Is there a benefit to sentinel lymph node biopsy in patients with T4 melanoma?
(Wiley Subscription Services, Inc., A Wiley Company, 2009-12-15)
BACKGROUND: Controversy exists as to whether patients with thick (Breslow depth >4 mm), clinically lymph node-negative melanoma require sentinel lymph node (SLN) biopsy. The authors examined the impact of SLN biopsy on ...
Merkel cell carcinoma: Critical review with guidelines for multidisciplinary management
(Wiley Subscription Services, Inc., A Wiley Company, 2007-07-01)
Merkel cell carcinoma (MCC) is a relatively rare cutaneous malignancy that occurs predominantly in the older white population. The incidence of MCC appears to have tripled during the past 20 years; an increase that is ...
The impact of factors beyond Breslow depth on predicting sentinel lymph node positivity in melanoma
(Wiley Subscription Services, Inc., A Wiley Company, 2007-01-01)
BACKGROUND. In addition to Breslow depth, the authors previously described how increasing mitotic rate and decreasing age predicted sentinel lymph node (SLN) metastases in patients with melanoma. The objectives of the ...
An Interdisciplinary Approach to the Management of Basal Cell Carcinoma of the Head and Neck
(Blackwell Publishing Ltd, 1987-10)
At the University of Michigan the dermatologic surgeon works closely with the head and neck surgeon in resecting extensive cutaneous malignancies that could benefit from the combined skills of both surgical specialists. ...
Wide excision without radiation for desmoplastic melanoma
(Wiley Subscription Services, Inc., A Wiley Company, 2005-10-01)
BACKGROUND Adjuvant radiation has been proposed for the treatment of patients with desmoplastic melanoma, who reportedly have local recurrence rates as high as 40–60%. The authors investigated local recurrence rates at a ...
Interleukin-6 predicts recurrence and survival among head and neck cancer patients See editorial on pages 671–3, this issue.
(Wiley Subscription Services, Inc., A Wiley Company, 2008-08-15)
BACKGROUND. Increased pretreatment serum interleukin (IL)-6 levels among patients with head and neck squamous cell carcinoma (HNSCC) have been shown to correlate with poor prognosis, but sample sizes in prior studies have ...
Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2004-12-15)
BACKGROUND The survival of patients with head and neck squamous cell carcinoma (HNSCC) remains unaffected despite recent therapeutic advances. To reverse this trend, reliable and clinically applicable markers of tumor ...
A phase II evaluation of a 3-hour infusion of paclitaxel, cisplatin, and 5-fluorouracil in patients with advanced or recurrent squamous cell carcinoma of the head and neck
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07-15)
BACKGROUND. Previous data from an institutional pilot study in patients with advanced or recurrent squamous cell carcinoma of the head and neck (SCCHN) who received treated a combined chemotherapy regimen of paclitaxel, ...