Now showing items 61-70 of 174
Haploinsufficiency and reduced expression of genes localized to the 8p chromosomal region in human prostate tumors
(Wiley Subscription Services, Inc., A Wiley Company, 2003-07)
Cytogenetic and molecular studies have suggested that deletion or rearrangement of sequences that map to the short arm of chromosome 8 may be permissive for tumorigenesis in several organ systems, and in human prostate ...
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression
(Wiley Subscription Services, Inc., A Wiley Company, 2009-04-15)
The metalloproteinase ADAM15 is a multi-domain disintegrin protease that is upregulated in a variety of human cancers. ADAM15 mRNA and protein levels are increased in prostate cancer and its expression is significantly ...
Separation of retinoid-induced epidermal and dermal thickening from skin irritation
(Springer-Verlag; Springer-Verlag is a part of Springer Sciences + Business Media, 2003-11)
The ability of the synthetic retinoid MDI-301, in which the carboxylic acid of 9- cis -retinoic acid (9-cis-RA) is replaced with an ester linkage, to induce epidermal and dermal thickening and skin irritation (erythema and ...
Stromal factors involved in prostate carcinoma metastasis to bone
(Wiley Subscription Services, Inc., A Wiley Company, 2003-02-01)
BACKGROUND Prostate carcinoma (PC) frequently metastasizes to bone, where it causes significant morbidity and mortality. Stromal elements in the primary and metastatic target organs are important mediators of tumor cell ...
Hospital lymph node counts and survival after radical cystectomy The views expressed herein do not necessarily represent the views of Center for Medicare and Medicaid Services or the United States Government.
(Wiley Subscription Services, Inc., A Wiley Company, 2008-02-15)
BACKGROUND. Several studies suggest that patients in whom more lymph nodes are examined have improved survival after radical cystectomy for bladder cancer. Despite growing calls for using lymph node counts as a hospital ...
The quality of surgical pathology care for men undergoing radical prostatectomy in the U.S.
(Wiley Subscription Services, Inc., A Wiley Company, 2007-06-15)
BACKGROUND. The authors assessed adherence with the College of American Pathologists (CAP) radical prostatectomy (RP) practice protocol in a national sample of men who underwent RP for early-stage prostate cancer. METHODS. ...
Standardization of radical cystectomy: Time to count and be counted
(Blackwell Science Ltd, 2004-09)
Osteoblasts produce soluble factors that induce a gene expression pattern in non-metastatic prostate cancer cells, similar to that found in bone metastatic prostate cancer cells
(Wiley Subscription Services, Inc., A Wiley Company, 2002-04-01)
BACKGROUND Progressive prostate cancer typically metastasizes to bone where prostate cancer cells gain an osteoblast-like phenotype and induce osteoblastic metastases through unknown mechanisms. To investigate the biology ...
EGFR ligand switch in late stage prostate cancer contributes to changes in cell signaling and bone remodeling
(Wiley Subscription Services, Inc., A Wiley Company, 2009-04-01)
BACKGROUND Bone metastasis occurs frequently in advanced prostate cancer (PCa) patients; however, it is not known why this happens. The epidermal growth factor receptor (EGFR) ligand EGF is available to early stage PCa; ...
Bone metastatic LNCaP-derivative C4-2B prostate cancer cell line mineralizes in vitro
(John Wiley & Sons, Inc., 2001-05-15)
BACKGROUND Prostate cancer frequently metastasizes to bone. However, unlike many other tumors that produce osteolytic lesions, prostate cancer produces osteoblastic lesions through unknown mechanisms. In the current study, ...