Now showing items 31-40 of 51
Dose escalation of oral vinorelbine in combination with estramustine in hormone-refractory adenocarcinoma of the prostate Presented in part at the 39th annual meeting of the American Society of Clinical Oncology, Chicago, Illinois, May 30–June 3, 2003.
(Wiley Subscription Services, Inc., A Wiley Company, 2006-06-15)
BACKGROUND The primary objective of the current study was to identify the tolerable dose level of oral vinorelbine when given in combination with estramustine to men with hormone-refractory prostate cancer (HRPC). The ...
Randomized clinical trial of a family intervention for prostate cancer patients and their spouses
(Wiley Subscription Services, Inc., A Wiley Company, 2007-12-15)
BACKGROUND. Few intervention studies have been conducted to help couples manage the effects of prostate cancer and maintain their quality of life. The objective of this study was to determine whether a family-based ...
A phase II evaluation of a 3-hour infusion of paclitaxel, cisplatin, and 5-fluorouracil in patients with advanced or recurrent squamous cell carcinoma of the head and neck
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07-15)
BACKGROUND. Previous data from an institutional pilot study in patients with advanced or recurrent squamous cell carcinoma of the head and neck (SCCHN) who received treated a combined chemotherapy regimen of paclitaxel, ...
Utility of extended pattern prostate biopsies for tumor localization See editorial on pages 1500–1, this issue.
(Wiley Subscription Services, Inc., A Wiley Company, 2008-10-01)
BACKGROUND. Focal targeted therapy has been proposed as a potential treatment for localized prostate cancer in an attempt to reduce morbidity. However, these modalities rely heavily on accurate tumor localization to achieve ...
Racial treatment trends in localized/regional prostate carcinoma: 1992–1999
(Wiley Subscription Services, Inc., A Wiley Company, 2005-02-01)
BACKGROUND African-American men have a greater incidence of and mortality from prostate carcinoma compared with white men, and they are less likely to receive definitive therapy (radical prostatectomy or external beam ...
Five-year survival after surgical treatment for kidney cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2007-05-01)
BACKGROUND. Kidney cancer's rising incidence is largely attributable to the increased detection of small renal masses. Although surgery rates have paralleled this incidence trend, mortality continues to rise, calling into ...
Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases
(Wiley Subscription Services, Inc., A Wiley Company, 2008-09-01)
Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumor-induced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/Β-catenin signaling is ...
Randomized phase 2/3 trial of CpG oligodeoxynucleotide PF-3512676 alone or with dacarbazine for patients with unresectable stage III and IV melanoma
(Wiley Subscription Services, Inc., A Wiley Company, 2009-09-01)
BACKGROUND: The primary objective of this phase 2 study was to assess the objective response rate (complete response [CR] + partial responses [PR]), by Response Evaluation Criteria in Solid Tumors, of PF-3512676, a CpG ...
Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions
(Wiley Subscription Services, Inc., A Wiley Company, 2008-11-15)
Expression of parathyroid hormone-related protein (PTHrP) correlates with prostate cancer skeletal progression; however, the impact of prostate cancer-derived PTHrP on the microenvironment and osteoblastic lesions in ...
Risk factors for adverse outcomes after transurethral resection of bladder tumors
(Wiley Subscription Services, Inc., A Wiley Company, 2006)
BACKGROUND Risk factors for adverse outcomes after transurethral resection of bladder tumors (TURBT) have not been identified to date. Such information would facilitate preoperative risk stratification and case-mix–adjusted ...