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Browsing by Author

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    • The Cag pathogenicity island and interaction between TLR 2/ NOD 2 and NLRP 3 regulate IL ‐1β production in Helicobacter pylori infected dendritic cells 
      Kim, Dong‐jae; Park, Jong‐hwan; Franchi, Luigi; Backert, Steffen; Núñez, Gabriel (Wiley Periodicals, Inc., 2013-10)
      PDF file (1.8MB)

    • Caspaseâ 1 inflammasomes in infection and inflammation 
      Lamkanfi, Mohamed; Kanneganti, Thirumala‐devi; Franchi, Luigi; Núñez, Gabriel (Wiley Periodicals, Inc., 2007-08)
      PDF file (179.5KB)

    • Cholesterol‐dependent cytolysins induce rapid release of mature IL‐1β from murine macrophages in a NLRP3 inflammasome and cathepsin B‐dependent manner 
      Chu, Jessica; Thomas, L. Michael; Watkins, Simon C.; Franchi, Luigi; Núñez, Gabriel; Salter, Russell D. (Wiley Periodicals, Inc., 2009-11)
      PDF file (725.1KB)

    • CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor 
      Inohara, Naohiro; Koseki, Takeyoshi; Chen, Shu; Wu, Xiaoyu; Núñez, Gabriel (John Wiley & Sons, Ltd, 1998-05-01)
      PDF file (346KB)

    • A critical role of RICK/RIP2 polyubiquitination in Nod‐induced NF‐κB activation 
      Hasegawa, Mizuho; Fujimoto, Yukari; Lucas, Peter C; Nakano, Hiroyasu; Fukase, Koichi; Núñez, Gabriel; Inohara, Naohiro (John Wiley & Sons, Ltd, 2008-01-23)
      PDF file (520.6KB)

    • Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome 
      Reimer, Thornik; Shaw, Michael H.; Franchi, Luigi; Coban, Cevayir; Ishii, Ken J.; Akira, Shizuo; Horii, Toshihiro; Rodriguez, Ana; Núñez, Gabriel (WILEY-VCH Verlag, 2010-03)
      PDF file (236.6KB)

    • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) 
      Cossarizza, Andrea; Chang, Hyun‐dong; Radbruch, Andreas; Acs, Andreas; Adam, Dieter; Adam‐klages, Sabine; Agace, William W.; Aghaeepour, Nima; Akdis, Mübeccel; Allez, Matthieu; Almeida, Larissa Nogueira; Alvisi, Giorgia; Anderson, Graham; Andrä, Immanuel; Annunziato, Francesco; Anselmo, Achille; Bacher, Petra; Baldari, Cosima T.; Bari, Sudipto; Barnaba, Vincenzo; Barros‐martins, Joana; Battistini, Luca; Bauer, Wolfgang; Baumgart, Sabine; Baumgarth, Nicole; Baumjohann, Dirk; Baying, Bianka; Bebawy, Mary; Becher, Burkhard; Beisker, Wolfgang; Benes, Vladimir; Beyaert, Rudi; Blanco, Alfonso; Boardman, Dominic A.; Bogdan, Christian; Borger, Jessica G.; Borsellino, Giovanna; Boulais, Philip E.; Bradford, Jolene A.; Brenner, Dirk; Brinkman, Ryan R.; Brooks, Anna E. S.; Busch, Dirk H.; Büscher, Martin; Bushnell, Timothy P.; Calzetti, Federica; Cameron, Garth; Cammarata, Ilenia; Cao, Xuetao; Cardell, Susanna L.; Casola, Stefano; Cassatella, Marco A.; Cavani, Andrea; Celada, Antonio; Chatenoud, Lucienne; Chattopadhyay, Pratip K.; Chow, Sue; Christakou, Eleni; Čičin‐šain, Luka; Clerici, Mario; Colombo, Federico S.; Cook, Laura; Cooke, Anne; Cooper, Andrea M.; Corbett, Alexandra J.; Cosma, Antonio; Cosmi, Lorenzo; Coulie, Pierre G.; Cumano, Ana; Cvetkovic, Ljiljana; Dang, Van Duc; Dang‐heine, Chantip; Davey, Martin S.; Davies, Derek; De Biasi, Sara; Del Zotto, Genny; Dela Cruz, Gelo Victoriano; Delacher, Michael; Della Bella, Silvia; Dellabona, Paolo; Deniz, Günnur; Dessing, Mark; Di Santo, James P.; Diefenbach, Andreas; Dieli, Francesco; Dolf, Andreas; Dörner, Thomas; Dress, Regine J.; Dudziak, Diana; Dustin, Michael; Dutertre, Charles‐antoine; Ebner, Friederike; Eckle, Sidonia B. G.; Edinger, Matthias; Eede, Pascale; Ehrhardt, Götz R.a.; Eich, Marcus; Engel, Pablo; Engelhardt, Britta; Erdei, Anna; Esser, Charlotte; Everts, Bart; Evrard, Maximilien; Falk, Christine S.; Fehniger, Todd A.; Felipo‐benavent, Mar; Ferry, Helen; Feuerer, Markus; Filby, Andrew; Filkor, Kata; Fillatreau, Simon; Follo, Marie; Förster, Irmgard; Foster, John; Foulds, Gemma A.; Frehse, Britta; Frenette, Paul S.; Frischbutter, Stefan; Fritzsche, Wolfgang; Galbraith, David W.; Gangaev, Anastasia; Garbi, Natalio; Gaudilliere, Brice; Gazzinelli, Ricardo T.; Geginat, Jens; Gerner, Wilhelm; Gherardin, Nicholas A.; Ghoreschi, Kamran; Gibellini, Lara; Ginhoux, Florent; Goda, Keisuke; Godfrey, Dale I.; Goettlinger, Christoph; González‐navajas, Jose M.; Goodyear, Carl S.; Gori, Andrea; Grogan, Jane L.; Grummitt, Daryl; Grützkau, Andreas; Haftmann, Claudia; Hahn, Jonas; Hammad, Hamida; Hämmerling, Günter; Hansmann, Leo; Hansson, Goran; Harpur, Christopher M.; Hartmann, Susanne; Hauser, Andrea; Hauser, Anja E.; Haviland, David L.; Hedley, David; Hernández, Daniela C.; Herrera, Guadalupe; Herrmann, Martin; Hess, Christoph; Höfer, Thomas; Hoffmann, Petra; Hogquist, Kristin; Holland, Tristan; Höllt, Thomas; Holmdahl, Rikard; Hombrink, Pleun; Houston, Jessica P.; Hoyer, Bimba F.; Huang, Bo; Huang, Fang‐ping; Huber, Johanna E.; Huehn, Jochen; Hundemer, Michael; Hunter, Christopher A.; Hwang, William Y. K.; Iannone, Anna; Ingelfinger, Florian; Ivison, Sabine M; Jäck, Hans‐martin; Jani, Peter K.; Jávega, Beatriz; Jonjic, Stipan; Kaiser, Toralf; Kalina, Tomas; Kamradt, Thomas; Kaufmann, Stefan H. E.; Keller, Baerbel; Ketelaars, Steven L. C.; Khalilnezhad, Ahad; Khan, Srijit; Kisielow, Jan; Klenerman, Paul; Knopf, Jasmin; Koay, Hui‐fern; Kobow, Katja; Kolls, Jay K.; Kong, Wan Ting; Kopf, Manfred; Korn, Thomas; Kriegsmann, Katharina; Kristyanto, Hendy; Kroneis, Thomas; Krueger, Andreas; Kühne, Jenny; Kukat, Christian; Kunkel, Désirée; Kunze‐schumacher, Heike; Kurosaki, Tomohiro; Kurts, Christian; Kvistborg, Pia; Kwok, Immanuel; Landry, Jonathan; Lantz, Olivier; Lanuti, Paola; LaRosa, Francesca; Lehuen, Agnès; Leibundgut‐landmann, Salomé; Leipold, Michael D.; Leung, Leslie Y.T.; Levings, Megan K.; Lino, Andreia C.; Liotta, Francesco; Litwin, Virginia; Liu, Yanling; Ljunggren, Hans‐gustaf; Lohoff, Michael; Lombardi, Giovanna; Lopez, Lilly; López‐botet, Miguel; Lovett‐racke, Amy E.; Lubberts, Erik; Luche, Herve; Ludewig, Burkhard; Lugli, Enrico; Lunemann, Sebastian; Maecker, Holden T.; Maggi, Laura; Maguire, Orla; Mair, Florian; Mair, Kerstin H.; Mantovani, Alberto; Manz, Rudolf A.; Marshall, Aaron J.; Martínez‐romero, Alicia; Martrus, Glòria; Marventano, Ivana; Maslinski, Wlodzimierz; Matarese, Giuseppe; Mattioli, Anna Vittoria; Maueröder, Christian; Mazzoni, Alessio; McCluskey, James; McGrath, Mairi; McGuire, Helen M.; McInnes, Iain B.; Mei, Henrik E.; Melchers, Fritz; Melzer, Susanne; Mielenz, Dirk; Miller, Stephen D.; Mills, Kingston H.G.; Minderman, Hans; Mjösberg, Jenny; Moore, Jonni; Moran, Barry; Moretta, Lorenzo; Mosmann, Tim R.; Müller, Susann; Multhoff, Gabriele; Muñoz, Luis Enrique; Münz, Christian; Nakayama, Toshinori; Nasi, Milena; Neumann, Katrin; Ng, Lai Guan; Niedobitek, Antonia; Nourshargh, Sussan; Núñez, Gabriel; O’Connor, José‐enrique; Ochel, Aaron; Oja, Anna; Ordonez, Diana; Orfao, Alberto; Orlowski‐oliver, Eva; Ouyang, Wenjun; Oxenius, Annette; Palankar, Raghavendra; Panse, Isabel; Pattanapanyasat, Kovit; Paulsen, Malte; Pavlinic, Dinko; Penter, Livius; Peterson, Pärt; Peth, Christian; Petriz, Jordi; Piancone, Federica; Pickl, Winfried F.; Piconese, Silvia; Pinti, Marcello; Pockley, A. Graham; Podolska, Malgorzata Justyna; Poon, Zhiyong; Pracht, Katharina; Prinz, Immo; Pucillo, Carlo E. M.; Quataert, Sally A.; Quatrini, Linda; Quinn, Kylie M.; Radbruch, Helena; Radstake, Tim R. D. J.; Rahmig, Susann; Rahn, Hans‐peter; Rajwa, Bartek; Ravichandran, Gevitha; Raz, Yotam; Rebhahn, Jonathan A.; Recktenwald, Diether; Reimer, Dorothea; Reis e Sousa, Caetano; Remmerswaal, Ester B.M.; Richter, Lisa; Rico, Laura G.; Riddell, Andy; Rieger, Aja M.; Robinson, J. Paul; Romagnani, Chiara; Rubartelli, Anna; Ruland, Jürgen; Saalmüller, Armin; Saeys, Yvan; Saito, Takashi; Sakaguchi, Shimon; Sala‐de‐oyanguren, Francisco; Samstag, Yvonne; Sanderson, Sharon; Sandrock, Inga; Santoni, Angela; Sanz, Ramon Bellmàs; Saresella, Marina; Sautes‐fridman, Catherine; Sawitzki, Birgit; Schadt, Linda; Scheffold, Alexander; Scherer, Hans U.; Schiemann, Matthias; Schildberg, Frank A.; Schimisky, Esther; Schlitzer, Andreas; Schlosser, Josephine; Schmid, Stephan; Schmitt, Steffen; Schober, Kilian; Schraivogel, Daniel; Schuh, Wolfgang; Schüler, Thomas; Schulte, Reiner; Schulz, Axel Ronald; Schulz, Sebastian R.; Scottá, Cristiano; Scott‐algara, Daniel; Sester, David P.; Shankey, T. Vincent; Silva‐santos, Bruno; Simon, Anna Katharina; Sitnik, Katarzyna M.; Sozzani, Silvano; Speiser, Daniel E.; Spidlen, Josef; Stahlberg, Anders; Stall, Alan M.; Stanley, Natalie; Stark, Regina; Stehle, Christina; Steinmetz, Tobit; Stockinger, Hannes; Takahama, Yousuke; Takeda, Kiyoshi; Tan, Leonard; Tárnok, Attila; Tiegs, Gisa; Toldi, Gergely; Tornack, Julia; Traggiai, Elisabetta; Trebak, Mohamed; Tree, Timothy I.M.; Trotter, Joe; Trowsdale, John; Tsoumakidou, Maria; Ulrich, Henning; Urbanczyk, Sophia; Veen, Willem; Broek, Maries; Pol, Edwin; Van Gassen, Sofie; Van Isterdael, Gert; Lier, René A.w.; Veldhoen, Marc; Vento‐asturias, Salvador; Vieira, Paulo; Voehringer, David; Volk, Hans‐dieter; Borstel, Anouk; Volkmann, Konrad; Waisman, Ari; Walker, Rachael V.; Wallace, Paul K.; Wang, Sa A.; Wang, Xin M.; Ward, Michael D.; Ward‐hartstonge, Kirsten A; Warnatz, Klaus; Warnes, Gary; Warth, Sarah; Waskow, Claudia; Watson, James V.; Watzl, Carsten; Wegener, Leonie; Weisenburger, Thomas; Wiedemann, Annika; Wienands, Jürgen; Wilharm, Anneke; Wilkinson, Robert John; Willimsky, Gerald; Wing, James B.; Winkelmann, Rieke; Winkler, Thomas H.; Wirz, Oliver F.; Wong, Alicia; Wurst, Peter; Yang, Jennie H. M.; Yang, Juhao; Yazdanbakhsh, Maria; Yu, Liping; Yue, Alice; Zhang, Hanlin; Zhao, Yi; Ziegler, Susanne Maria; Zielinski, Christina; Zimmermann, Jakob; Zychlinsky, Arturo (Wiley, 2019-10)
      PDF file (43.9MB) PDF file (70.9MB)

    • Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease 
      Pickard, Joseph M.; Zeng, Melody Y.; Caruso, Roberta; Núñez, Gabriel (Wiley Periodicals, Inc., 2017-09)
      PDF file (863.8KB) PDF file (486.2KB)

    • harakiri , a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival‐promoting proteins Bcl‐2 and Bcl‐X L 
      Inohara, Naohiro; Ding, Liyun; Chen, Shu; Núñez, Gabriel (John Wiley & Sons, Ltd, 1997-04-01)
      PDF file (442.2KB)

    • Identification and functional characterization of EseH, a new effector of the type III secretion system of Edwardsiella piscicida 
      Hou, Mingyu; Chen, Ran; Yang, Dahai; Núñez, Gabriel; Wang, Zhuang; Wang, Qiyao; Zhang, Yuanxing; Liu, Qin (Wiley Periodicals, Inc., 2017-01)
      PDF file (5.5MB) PDF file (945.1KB)

    • Induction of adaptive immunity by flagellin does not require robust activation of innate immunity 
      Sanders, Catherine J.; Franchi, Luigi; Yarovinsky, Felix; Uematsu, Satoshi; Akira, Shizuo; Núñez, Gabriel; Gewirtz, Andrew T. (WILEY-VCH Verlag, 2009-02)
      PDF file (356.5KB)

    • Inflammasomes as microbial sensors 
      Franchi, Luigi; Muñoz-Planillo, Raul; Reimer, Thornik; Eigenbrod, Tatjana; Núñez, Gabriel (WILEY-VCH Verlag, 2010-03)
      PDF file (139.5KB)

    • Inhibition of B-cell death does not restore T-cell-dependent immune responses in CD40-deficient mice 
      Merino, Jesús; Díez, Miguel A.; Muñiz, María; Buelta, Luis; Núñez, Gabriel; López-Hoyos, Marcos; Merino, Ramón (Blackwell Science, Ltd, 2003-08)
      PDF file (223.3KB)

    • Innate immune recognition of flagellin limits systemic persistence of B rucella 
      Terwagne, Matthieu; Ferooz, Jonathan; Rolán, Hortensia G.; Sun, Yao‐hui; Atluri, Vidya; Xavier, Mariana N.; Franchi, Luigi; Núñez, Gabriel; Legrand, Thomas; Flavell, Richard A.; De Bolle, Xavier; Letesson, Jean‐jacques; Tsolis, Renée M. (John Wiley & Sons, 2013-06)
      PDF file (1023.3KB)

    • Intracellular NOD-like receptors in innate immunity, infection and disease 
      Franchi, Luigi; Park, Jong-Hwan; Shaw, Michael H.; Marina-Garcia, Noemi; Chen, Grace; Kim, Yun-Gi; Núñez, Gabriel (Blackwell Publishing Ltd, 2008-01)
      PDF file (293.5KB)

    • Intracellular sensors of microbes and danger 
      Núñez, Gabriel (Blackwell Publishing LtdWiley Periodicals, Inc., 2011-09)
      PDF file (221.3KB)

    • Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils 
      Jeong, Yu‐jin; Kang, Min‐jung; Lee, Sang‐jin; Kim, Chang‐hwan; Kim, Jee‐cheon; Kim, Tae‐hyoun; Kim, Dong‐jae; Kim, Donghyun; Núñez, Gabriel; Park, Jong‐hwan (Wiley Periodicals, Inc., 2014-10)
      PDF file (407.3KB)

    • NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages 
      Brooks, Michelle N.; Rajaram, Murugesan V. S.; Azad, Abul K.; Amer, Amal O.; Valdivia‐arenas, Martin A.; Park, Jong‐hwan; Núñez, Gabriel; Schlesinger, Larry S. (Wiley Periodicals, Inc.Blackwell Publishing Ltd, 2011-03)
      PDF file (763.9KB)

    • The protein kinase PKR is critical for LPS‐induced iNOS production but dispensable for inflammasome activation in macrophages 
      He, Yuan; Franchi, Luigi; Núñez, Gabriel (Wiley Periodicals, Inc., 2013-04)
      PDF file (776.5KB)

    • A putative role for human BFK in DNA damage-induced apoptosis 
      Özören, Nesrin; Inohara, Naohiro; Núñez, Gabriel (WILEY-VCH Verlag, 2009-07)
      PDF file (1.2MB)

    • Recognition of the microbiota by Nod2 contributes to the oral adjuvant activity of cholera toxin through the induction of interleukin-1β 
      Kim, Donghyun; Kim, Yu‐mi; Kim, Wan‐uk; Park, Jong‐hwan; Núñez, Gabriel; Seo, Sang‐uk (Wiley Periodicals, Inc., 2019-11)
      PDF file (369.9KB) PDF file (504.5KB)

    • Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition 
      Tanabe, Tsuyoshi; Chamaillard, Mathias; Ogura, Yasunori; Zhu, Li; Qiu, Su; Masumoto, Junya; Ghosh, Partho; Moran, Anthony; Predergast, Martina M; Tromp, Gerard; Williams, Charlene J; Inohara, Naohiro; Núñez, Gabriel (John Wiley & Sons, Ltd, 2004-04-07)
      PDF file (593.1KB) PDF file (69.7KB) PDF file (109.1KB) PDF file (94.2KB) PDF file (80.9KB)

    • Role of cytochrome c and dATP/ATP hydrolysis in Apaf‐1‐mediated caspase‐9 activation and apoptosis 
      Hu, Yuanming; Benedict, Mary A.; Ding, Liyun; Núñez, Gabriel (John Wiley & Sons, Ltd, 1999-07-01)
      PDF file (254.9KB)

    • Targeting cancer cell death with a bcl-x S adenovirus 
      Han, Jeffrey S.; Wicha, Max S.; Núñez, Gabriel; Clarke, Michael F. (Springer-Verlag, 1998-09)
      PDF file (720KB)

    • The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls 
      Moreira, Lilian O.; El Kasmi, Karim C.; Smith, Amber M.; Finkelstein, David; Fillon, Sophie; Kim, Yun-Gi; Núñez, Gabriel; Tuomanen, Elaine; Murray, Peter J. (Blackwell Publishing Ltd, 2008-10)
      PDF file (697.2KB)