Research data supporting, 'Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Meta-Iodobenzylguanidine Derivatives for Enhanced Cellular Internalization', 10.1021/acsmaterialslett.3c00781, AuNP = Au nanoparticle.
In 10.1021/acsmaterialslett.3c00781, we report the synthesis and application of two metaiodobenzylguanidine (MIBG) derivatives decorated on the surface of AuNPs at high molar ratios; greatly enhanced cellular uptake is observed across neuroblastoma (NB), HeLa, and HEK cell lines.
This dataset consists of synthetic NMR and mass spec data for the small molecules and their intermediates, dark-field microscopy data, inductively-coupled plasma mass spectrometry data, and raw data for characterizing the AuNPs (TEM, DLS, zeta potential).
Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Metaiodobenzylguanidine Derivatives for Enhanced Cellular Internalization Natalie S. Potter, Alan McLean, Evan C. Bornowski, Thomas Hopkins, Jingyi Luo, John P. Wolfe, Wei Qian, and Raoul Kopelman ACS Materials Letters Article ASAP DOI: 10.1021/acsmaterialslett.3c00781
This is the experimental data referenced in our manuscript entitled "Influence of CUREs on STEM retention depends on demographic identities." The dataset comprises csv files with results from student surveys given to students enrolled in Biology 173 from Fall 2015 through Fall 2019 as well as institutional data of their course grades and cumulative GPA at the time they enrolled in Biology 173, and graduation and major data for student who had graduated by 2021. The survey questions used in the analysis and the IRB consent form are also included as pdfs.
Bradshaw, L., Vernon J., Schmidt T., James T., Zhang J., Archbold H., Cadigan K., Wolfe J.P. & Goldberg D. 2023. Research article: Influence of CUREs on STEM retention depends on demographic identities. J Microbiol Biol Educ (accepted)
