This dataset includes a catalog of events for the 2019 Ridgecrest, CA earthquake sequence with calibrated relative moment magnitude estimates. We include results from all cases described in Gable and Huang 2024b.
Gable, S.L., and Y. Huang (2024). Quantifying Magnitude Uncertainty of the 2019 Ridgecrest Earthquake Sequence Through a Sensitivity Study of the Relative Magnitude Method. Bull. Seismol. Soc. Am. (in production)
We study the pathophysiology of spinal cord decompression sickness. We saturated ex-vivo bovine spinal cord tissue with nitrogen, partially decompressed the samples to induce bubble formation, and then probed the mechanical response of the surrounding tissue by pressure-cycling.
Reconstructed CT slices for Cranium of Castoroides (University of Michigan Museum of Paleontology catalog number UMMP VP 3110) as a series of TIFF images. Raw projections are not included in this dataset. The reconstructed slice data resulting from a merge of two separate scans are offered here as a series of unsigned 16-bit integer TIFF images. There may be slight differences in voxel grey values between the two parts. The upper left corner of the first image (*_0000.tif) is the XYZ origin.
Reconstructed CT slices for Cranium of Castoroides (University of Michigan Museum of Paleontology catalog number UMMP VP 3110) as a series of TIFF images. Raw projections are not included in this dataset. The reconstructed slice data from the scan are offered here as a series of unsigned 16-bit integer TIFF images. The upper left corner of the first image (*_0000.tif) is the XYZ origin.
Reconstructed CT slices for Cranium of Castoroides (University of Michigan Museum of Paleontology catalog number UMMP VP 3110) as a series of TIFF images. Raw projections are not included in this dataset. The reconstructed slice data from the scan are offered here as a series of unsigned 16-bit integer TIFF images. The upper left corner of the first image (*_0000.tif) is the XYZ origin.
The survival and beta models forecasting ice cover around the Apostle Island National Lakeshore use Lake Superior surface water temperature data collected from the Great Lakes Environmental Research Laboratory (GLERL). GLERL hosts Lake Superior surface water temperature data pre-1995 from the Large Lake Thermodynamics Model (LLTM) and post-1995 from the Great Lakes Surface Environmental Analysis (GLSEA). The pre-1995 data is currently being moved and is unavailable from GLERL, and therefore, the (entire) surface water temperature record used by the models is hosted here. Please see the methods for direct data access links.
The LLTM, the source of the pre-1995 data, is described in Croley II, T. E., & Assel, R. A. (1994). A one-dimensional ice thermodynamics model for the Laurentian Great Lakes. Water Resources Research, 30(3), 625–639. Documentation on GLSEA can be found on their website.
LSD1 histone H3K4 demethylase and its binding partner PHF21A, a reader protein for unmethylated H3K4, both undergo neuron-specific microexon splicing. The LSD1 neuronal microexon weakens H3K4 demethylation activity and can alter the substrate specificity to H3K9 or H4K20. Meanwhile, the PHF21A neuronal microexon interferes with nucleosome binding. However, the temporal expression patterns of LSD1 and PHF21A splicing isoforms during brain development remain unknown. In this work, we report that neuronal PHF21A isoform expression precedes neuronal LSD1 isoform expression during human neuron differentiation and mouse brain development. The asynchronous splicing events resulted in stepwise deactivation of the LSD1-PHF21A complex in reversing H3K4 methylation. We further show that the enzymatically inactive LSD1-PHF21A complex interacts with neuron-specific binding partners, including MYT1-family transcription factors and post-transcriptional mRNA processing proteins such as VIRMA. The interaction with the neuron-specific components, however, did not require the PHF21A microexon, indicating that the neuronal proteomic milieu, rather than the microexon-encoded PHF21A segment, is responsible for neuron-specific complex formation. These results indicate that the PHF21A microexon is dispensable for neuron-specific protein-protein interactions, yet the enzymatically inactive LSD1-PHF21A complex might have unique gene-regulatory roles in neurons.
Citation to related publication:
Nagai, M., Porter, R. S., Miyasato, M., Wang, A., Gavilan, C. M., Hughes, E. D., Wu, M. C., Saunders, T. L., Iwase, S. Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. Journal of Biological Chemistry (2024).
Images of droplet dynamics during and after optical excitation experiments were recorded in the ultra-fast regime at 1 million frames per second (fps) while the low-speed, quasi-static evolution was carried at 1 fps. During both the inertial and quasi-static phases, we record 1–3 frames in the reference configuration prior to the arrival of the laser-pulse to distinguish the bubble from the background. Lastly, due to the complex physics of plasma formation and chemistry, forward simulations begin at the time when the bubble reaches its maximum expansion
Abeid, Bachir A, et al. (2024). Experimental and numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials
