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- Creator:
- Nason, Samuel R., Vaskov, Alex K., Willsey, Matthew S., Welle, Elissa J., An, Hyochan, Vu, Philip P., Bullard, Autumn J., Nu, Chrono S., Kao, Jonathan C., Shenoy, Krishna V., Jang, Taekwang, Kim, Hun-Seok, Blaauw, David, Patil, Parag G., and Chestek, Cynthia A.
- Description:
- This data is a subset of the data used to generate figures similar to figures 1, 2, 3, and 4 in Nason et al., 2020, Nature Biomedical Engineering. The purpose of the study was to demonstrate the benefits of using spiking band power, a low-power but single unit specific recording signal, for brain-machine interfaces with nonhuman primates with the potential to impact low-power brain-machine interfaces with humans. All of the data is contained in .mat files, which can be commonly opened by Matlab and the Python scipy library.
- Keyword:
- Brain-machine interface, Prosthesis, and Neural recording
- Citation to related publication:
- Nason, S.R., Vaskov, A.K., Willsey, M.S., Welle, E.J., An, H., Vu, P.P., Bullard, A.J., Nu, C.S., Kao, J.C., Shenoy, K.V., Jang, T., Kim, H.-S., Blaauw, D., Patil, P.G., and Chestek, C.A. (2020). A low-power band of neuronal spiking activity dominated by local single units improves the performance of brain–machine interfaces. Nat. Biomed. Eng. 4, 973–983. https://doi.org/10.1038/s41551-020-0591-0
- Discipline:
- Engineering
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- Creator:
- Nason, Samuel R., Mender, Matthew J., Vaskov, Alex K., Willsey, Matthew S., Ganesh Kumar, N., Kung, Theodore A., Patil, Parag G., and Chestek, Cynthia A.
- Description:
- This data is a subset of the data used to generate components of all figures in the manuscript and supplement in Nason et al., 2021, Neuron. The purpose of the study was to demonstrate the first-ever simultaneous brain-control of two independent groups of fingers in one hand with some analysis of cortical tuning to finger movements in nonhuman primates. This advises future brain-machine interfaces for the control of finger movements with humans. All of the data is contained in .mat files, which can be commonly opened by Matlab and the Python scipy library. The Matlab packages (and versions) used for the manuscript are: MATLAB (9.4), Signal Processing Toolbox (8.0), Statistics and Machine Learning Toolbox (11.3), and Curve Fitting Toolbox (3.5.7).
- Keyword:
- Brain-machine interface, Prosthesis, and Upper extremity
- Citation to related publication:
- Nason, S.R., Mender, M.J., Vaskov, A.K., Willsey, M.S., Ganesh Kumar, N., Kung, T.A., Patil, P.G., and Chestek, C.A. (2021). Real-Time Linear Prediction of Simultaneous and Independent Movements of Two Finger Groups Using an Intracortical Brain-Machine Interface. Neuron (accepted).
- Discipline:
- Engineering
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- Creator:
- Mohtat, Peyman, Siegel, Jason B., Stefanopoulou, Anna G., and Lee, Suhak
- Description:
- The focus of this research effort is to systematically study the capability of aging diagnostics using cell expansion under variety of aging conditions and states. The data collection campaign is very important to cover various degradation modes to extract the degradation features that will be used to inform, parameterize, and validate the models developed earlier. In the data collection campaign, we are documenting the evolution of the electrical and mechanical characteristics and especially the reversible mechanical measurement. It is important to note that we collect data using newly developed fixtures that enables the simultaneous measurement of mechanical and electrical response under pseudo-constant pressure.
- Keyword:
- Lithium-ion batteries, Mechanical response, Aging, NMC, and Pouch cells
- Citation to related publication:
- Peyman Mohtat et al. (2021). Reversible and Irreversible Expansion of Lithium-ion Batteries Under a Wide Range of Stress Factors. J. Electrochem. Soc. 168 100520 https://doi.org/10.1149/1945-7111/ac2d3e
- Discipline:
- Engineering
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- Creator:
- Revzen, Shai
- Description:
- This repository contains both the data and python3 code that reads this data and reproduces the relevant figures. The code depends on NumPy >1.17 and matplotlib >3.1 and was tested on python 3.8
- Keyword:
- locomotion, slipping, low Reynolds number, walking, and slithering
- Discipline:
- Science and Engineering
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- Creator:
- Arthurs, Christopher J., Khlebnikov, Rostislav, Melville, Alexander, Marčan, Marija, Gomez, Alberto, Dillon-Murphy, Desmond, Cuomo, Federica, Vieira, Miguel, Schollenberger, Jonas, Lynch, Sabrina, Tossas-Betancourt, Christopher, Iyer, Kritika, Hopper, Sara, Livingston, Elizabeth, Youssefi, Pouya, Noorani, Alia, Ben Ahmed, Sabrina, Nauta, Foeke J.N., van Bakel, Theodorus M.J., Ahmed, Yunus, van Bakel, Petrus A.J., Mynard, Jonathan, Di Achille, Paolo, Gharahi, Hamid, Lau, Kevin D., Filonova, Vasilina, Aguirre, Miquel, Nama, Nitesh, Xiao, Nan, Baek, Seungik, Garikipati, Krishna, Sahni, Onkar, Nordsletten, David, and Figueroa, Carlos A.
- Description:
- This repository contains the source code for the CRIMSON GUI, as required in the PLOS Computational Biology publication: CRIMSON: An Open-Source Software Framework for Cardiovascular Integrated Modelling and Simulation by the same authors., This is a snapshot of the software; build dependencies can be found at https://doi.org/10.7302/ssj9-n788. Please visit https://github.com/carthurs/CRIMSONGUI/releases/tag/PLOS_Comp_Bio & www.crimson.software for more general information and the most up to date version of the software., and Software can be compiled in Windows.
- Keyword:
- Blood Flow Simulation, Patient-specific, Open-source Software, Image-based simulation, Cardiovascular Medical Image, Segmentation, and Finite Element Simulation
- Citation to related publication:
- CRIMSON: An Open-Source Software Framework for Cardiovascular Integrated Modelling and Simulation C.J. Arthurs, R. Khlebnikov, A. Melville, M. Marčan, A. Gomez, D. Dillon-Murphy, F. Cuomo, M.S. Vieira, J. Schollenberger, S.R. Lynch, C. Tossas-Betancourt, K. Iyer, S. Hopper, E. Livingston, P. Youssefi, A. Noorani, S. Ben Ahmed, F.J.H. Nauta, T.M.J. van Bakel, Y. Ahmed, P.A.J. van Bakel, J. Mynard, P. Di Achille, H. Gharahi, K. D. Lau, V. Filonova, M. Aguirre, N. Nama, N. Xiao, S. Baek, K. Garikipati, O. Sahni, D. Nordsletten, C.A. Figueroa bioRxiv 2020.10.14.339960; doi: https://doi.org/10.1101/2020.10.14.339960 and Computational Vascular Biomechanics Lab @ the University of Michigan and other collaborators, The Qt Company, NSIS Team and contributors, PostgreSQL Global Development Group, Oracle Corporation, Kitware. CRIMSON open source project - Build Dependencies [Data set], (2021). University of Michigan - Deep Blue. https://doi.org/10.7302/ssj9-n788
- Discipline:
- Health Sciences and Engineering
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- Creator:
- Ramasubramani, Vyas
- Description:
- The goal of the work is to elucidate the stability of a complex experimentally observed structure of proteins. We found that supercharged GFP molecules spontaneously assemble into a complex 16-mer structure that we term a protomer, and that under the right conditions an even larger assembly is observed. The protomer structure is very well defined, and we performed simulations to try and understand the mechanics underlying its behavior. In particular, we focused on understanding the role of electrostatics in this system and how varying salt concentrations would alter the stability of the structure, with the ultimate goal of predicting the effects of various mutations on the stability of the structure. There are two separate projects included in this repository, but the two are closely linked. One, the candidate_structures folder, contains the atomistic outputs used to generate coarse-grained configurations. The actual coarse-grained simulations are in the rigid_protein folder, which pulls the atomistic coordinates from the other folder. All data is managed by signac and lives in the workspace directories, which contain various folders corresponding to different parameter combinations. The parameters associated with a given folder are stored in the signac_statepoint.json files within each subdirectory. The atomistic data uses experimentally determined protein structures as a starting point; all of these are stored in the ConfigFiles folder. The primary output is the topology files generated from the PDBs by GROMACS; these topologies are then used to parametrize the Monte Carlo simulations. In some cases, atomistic simulations were actually run as well, and the outputs are stored alongside the topology files. In the rigid_protein folder, the ConfigFiles folder contains MSMS, the software used to generate polyhedral representations of proteins from the PDBs in the candidate_structures folder. All of the actual polyhedral structures are also stored in the ConfigFiles folder. The actual simulation trajectories are stored as general simulation data (GSD) files within each subdirectory of the workspace, along with a single .pos file that contains the shape definition of the (nonconvex) polyhedron used to represent a protein. The logged quantities, such as energies and MC move sizes, are stored in .log files. The logic for the simulations in the candidate_structures project is in the Python scripts project.py, operations.py, and scripts/init.py. The rigid_protein folder also includes the notebooks directory, which contains Jupyter notebooks used to perform analyses, as well as the Python scripts used to actually perform the simulations and manage the data space. In particular, the project.py, operations.py and scripts/init.py scripts contain most of the logic associated with the simulations.
- Keyword:
- Protein assembly, Cryo TEM, Hierarchical Assembly, Monte Carlo simulation, and Coarse-grained simulation
- Citation to related publication:
- Anna J Simon, Vyas Ramasubramani, Jens Glaser, Arti Pothukuchy, Jillian Gerberich, Janelle Leggere, Barrett R Morrow, Jimmy Golihar, Cheulhee Jung, Sharon C Glotzer, David W Taylor, Andrew D Ellington,"Supercharging enables organized assembly of synthetic biomolecules," bioRxiv 323261; doi: https://doi.org/10.1101/323261
- Discipline:
- Science and Engineering
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- Creator:
- Reed, Matthew P., Boyle, K.
- Description:
- This is the first physical anthropomorphic test device to be based both on statistical body shape models as well as 3D printing.
- Keyword:
- Child Belt Fit Manikin
- Citation to related publication:
- Reed, M.P. and Boyle, K.J. (2017). Development of a manikin representing a two‐year‐old child for belt‐fit measurement. Proc. 2017 IRCOBI Conference. Antwerp, Belgium. https://trid.trb.org/view/1486130 and Kim, K.H., Jones, M.L.H., Ebert, S.M., Malik, L., Manary, M.A., Reed, M.P., and Klinich, K.D. (2015). Development of Virtual Toddler Fit Models for Child Safety Restraint Design. Technical Report UMTRI-2015-38. University of Michigan Transportation Research Institute, Ann Arbor, MI.
- Discipline:
- Engineering
-
- Creator:
- Isaacoff, Benjamin P., Li, Yilai, Lee, Stephen A., and Biteen, Julie S.
- Description:
- This is the experimental data referenced in our manuscript entitled “SMALL-LABS: An algorithm for measuring single molecule intensity and position in the presence of obscuring backgrounds .” These live-cell single-molecule imaging movies were used as a test of the SMALL-LABS single-molecule image analysis algorithm. The dataset comprises two movies; each one is provided both as a .tif stack and as an .avi file. The movie called “low_bg” has a standard low background, and the movie called “high_bg” includes a high fluorescent background produced by an external 488-nm laser.
- Keyword:
- single-molecule, microscopy, image analysis, mirobiology, and bacteria
- Citation to related publication:
- B.P. Isaacoff, Y. Li, S.A. Lee, J.S. Biteen, "SMALL-LABS: Measuring Single-Molecule Intensity and Position in Obscuring Backgrounds." Biophysical Journal, 975-982, 116, 2019. https://doi.org/10.1016/j.bpj.2019.02.006
- Discipline:
- Engineering and Science
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- Creator:
- Mirshams Shahshahani, Payam
- Description:
- Investigating minimum human reaction times is often confounded by the motivation, training, and state of arousal of the subjects. We used the reaction times of athletes competing in the shorter sprint events in the Athletics competitions in recent Olympics (2004-2016) to determine minimum human reaction times because there's little question as to their motivation, training, or state of arousal. The reaction times of sprinters however are only available on the IAAF web page for each individual heat, in each event, at each Olympic. Therefore we compiled all these data into two separate excel sheets which can be used for further analyses.
- Keyword:
- minimum reaction time, sprinter, Olympics, Athletics, sex difference, starting block, and false start
- Citation to related publication:
- Mirshams Shahshahani P, Lipps DB, Galecki AT, Ashton-Miller JA (2018) On the apparent decrease in Olympic sprinter reaction times. PLoS ONE 13(6): e0198633. https://doi.org/10.1371/journal.pone.0198633
- Discipline:
- Engineering, Health Sciences, Science, Other, and General Information Sources
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- Creator:
- Nguyen, Thanh H., Wright, Mason, Wellman, Michael P., and Singh, Satinder
- Description:
- In this work , we study the problem of allocating limited security countermeasures to protect network data from cyber-attacks, for scenarios modeled by Bayesian attack graphs. We consider multi-stage interactions between a network administrator and cybercriminals, formulated as a security game. We propose parameterized heuristic strategies for the attacker and defender and provide detailed analysis of their time complexity. Our heuristics exploit the topological structure of attack graphs and employ sampling methods to overcome the computational complexity in predicting opponent actions. Due to the complexity of the game, we employ a simulation-based approach and perform empirical game analysis over an enumerated set of heuristic strategies. Finally, we conduct experiments in various game settings to evaluate the performance of our heuristics in defending networks, in a manner that is robust to uncertainty about the security environment.
- Keyword:
- Empirical Game-Theoretic Analysis, Multi-stage Security Games, Attack Graph, Game Theory, and Moving Target Defense
- Citation to related publication:
- Nguyen, T. H., Wright, M., Wellman, M. P., & Singh, S. (2017). Multi-stage attack graph security games: Heuristic strategies, with empirical game-theoretic analysis. In MTD 2017 - Proceedings of the 2017 Workshop on Moving Target Defense, co-located with CCS 2017 (Vol. 2017-January, pp. 87-97). Association for Computing Machinery, Inc. https://doi.org/10.1145/3140549.3140562
- Discipline:
- Science and Engineering