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Zagorë
User Collection
- Creator:
- Galaty, Michael
- Description:
- The following works contain the databases, field notebooks, unit and profile drawings, photographs, photo descriptions, radiocarbon dates, and geophysical survey data related to the Zagorë settlement excavation.
- Keyword:
- archaeology
- Discipline:
- Science and Humanities
4Works -
- Creator:
- Hatch, Nan E.
- Description:
- Craniosynostosis is the premature fusion of cranial bones. The goal of this study was to determine if delivery of recombinant tissue nonspecific alkaline phosphatase (TNAP) could prevent or diminish the severity of craniosynostosis in a C57BL/6 FGFR2C342Y/+ model of neonatal onset craniosynostosis or a BALB/c FGFR2C342Y/+ model of postnatal onset craniosynostosis. Mice were injected with a lentivirus encoding a mineral targeted form of TNAP immediately after birth. Cranial bone fusion as well as cranial bone volume, mineral content and density were assessed by micro computed tomography. Craniofacial shape was measured with calipers., Alkaline phosphatase, alanine amino transferase (ALT) and aspartate amino transferase (AST) activity levels were measured in serum. Neonatal delivery of TNAP diminished craniosynostosis severity from 94% suture obliteration in vehicle treated mice to 67% suture obliteration in treated mice, p<0.02) and the incidence of malocclusion from 82.4% to 34.7% (p<0.03), with no effect on cranial bone in C57BL/6 FGFR2C342Y/+ mice. In contrast, treatment with TNAP improved cranial bone volume (p< 0.01), density (p< 0.01) and mineral content (p< 0.01) but had no effect on craniosynostosis or malocclusion in BALB/c FGFR2C342Y/+ mice. , These results indicate that post-natal recombinant TNAP enzyme therapy diminishes craniosynostosis severity in the C57BL/6 FGFR2C342Y/+ neonatal onset mouse model of Crouzon syndrome, and that effects of exogenous TNAP are genetic background dependent., and Included in this collection is one set of images representing the C57BL/6 FGFR2C342Y/+ model of neonatal onset craniosynostosis, and one for the BALB/c FGFR2C342Y/+ model of postnatal onset craniosynostosis
- Keyword:
- craniofacial, bone, craniosynostosis, FGFR2, TNAP, mouse model, and development
- Discipline:
- Health Sciences
2Works -
Vani Region Archaeological Survey
User Collection
- Creator:
- Ratte, Christopher and Mokrisova, Jana
- Description:
- The data presented here were collected in the course of an archaeological survey of the region around Vani in the Republic of Georgia, carried out between 2009 and 2011, with follow-up visits in 2014 and 2017. The survey was sponsored by the University of Michigan, the Institute for the Study of the Ancient World at New York University, and the Otar Lordkipanidze Institute of Archaeological Research in Tbilisi. , The archaeological site of Vani lies in the territory of ancient Colchis, a triangular area bordered by the Black Sea to the west and by the greater and lesser Caucasus Mountains to the north and south – famous in Greek legend as the land of the Golden Fleece and the home of Medea. Vani itself is situated approximately 70 km inland, in the foothills of the lesser Caucasus. A regional culture recognizable on the evidence of distinctive traditions of pottery and metalworking and the appearance of a network of relatively large settlements had emerged in Colchis by the late second and early first millennia BC. , Vani is one of the most extensively studied archaeological sites in Colchis. Excavations have revealed a continuous occupation sequence extending from the 8th to the 1st centuries B.C. Especially notable are the rich and unusual graves of the Classical period (6th-4th centuries), the monumental stone architecture of the Hellenistic period (3rd to 1st centuries), especially fortifications enclosing an area of approximately 6 ha, and the extensive evidence for interaction with the Mediterranean and Near Eastern worlds, including not only commercial and luxury imports (Greek transport amphorae, fine bronze and silver utensils from both the Greek world and Persia), but also local production of bronze sculpture and one long Greek bronze inscription., In spite of the richness of the site, however, important questions about its purpose and function over time remain unresolved. How extensive was the ancient settlement? Was Vani an isolated stronghold, a regional population center, a sanctuary, or a combination of two or all three? How does it compare with other sites in Colchis? In addition to ongoing research at Vani itself, regional survey provides an obvious approach to some of these questions. In previous years, examination of a number of outlying sites had already yielded remains extending in date from the Early Bronze Age to the mediaeval period., and The purpose of the regional survey project begun in 2009 was to integrate existing knowledge about Vani and environs into the kind of technological and conceptual framework characteristic of contemporary American survey archaeology. Of particular importance was the use of Geographical Information Systems (GIS) as an organizational and analytical tool, and of geophysical prospection both in the immediate environs of Vani and at regional sites. Like all regional surveys, our project recorded evidence of all periods, from prehistory to the present day, but we were particularly interested in questions having to do with the increasing social complexity of Colchis in the mid- and later 1st millennium BC – when Greek explorers began to establish colonies on the Black Sea coast of Georgia, and the Persian empire pushed up against the mountains of the Caucasus. What was the nature of Colchian society in this period? How was it affected by interaction with the larger Greek, Persian, and Pontic worlds? And how can regional survey at Vani and throughout Colchis help us to address these questions?
- Keyword:
- Classical Archaeology, Fortifications, Churches, Sanctuaries, Quarries, Modern Settlements, Settlements, and Burials
- Discipline:
- Humanities
25Sub-collections1Works -
University of Michigan Museum of Zoology
User Collection
- Creator:
- University of Michigan Museum of Zoology
- Description:
- The University of Michigan Museum of Zoology (UMMZ) is the center for the study of animal diversity on campus, focusing on the evolutionary origins of the planet’s animal species, the genetic information they contain and the communities and ecosystems they help form. Now an integral part of the Department of Ecology and Evolutionary Biology (EEB), the UMMZ houses world-class collections, containing more than 15 million specimens, span almost 200 years of regional and global biodiversity studies and that support a multi-faceted Departmental research and teaching program.
- Discipline:
- Science
4Sub-collections0Works -
Transmission of Oral microbiome and Sequencing
User Collection
- Creator:
- Lee, Kyu Han
- Description:
- De-identified participant data from household transmission study of influenza in Nicaragua Oligotype count table and taxonomic classifications
- Keyword:
- Influenza and Microbiome
- Discipline:
- Health Sciences
2Works -
- Creator:
- University of Michigan Taubman College of Architecture & Urban Planning and University of Michigan College of Literature, Science, and the Arts
- Description:
- The Michigan–Mellon Project on the Egalitarian Metropolis supported several impactful programs and initiatives. These collaborative projects developed through several mediums, primarily: faculty and student-led research, public-engaged scholarship, and community-led place-based projects. Explore each project below! Original website at https://sites.lsa.umich.edu/egalitarianmetropolis/.
- Discipline:
- Humanities
13Works -
TCC Engine Collection
User Collection
- Creator:
- Schiffmann, Philipp, Reuss, David L, and Sick, Volker
- Description:
- This Collection is a compilation of data measured in the TCC engine at the University of Michigan, Department of Mechanical Engineering, Quantitative Laser Diagnostics Laboratory. The posted Work Deposits are never changed. However, this collection will be expanded with additional Work Deposits as new experimental data become available. The intent of the collection is to provide a comprehensive experimental data set from the TCC-III engine, for fundamental discovery research on in-cylinder flow and spark-ignited combustion. Also, to enable in-depth support for CFD development and validation. The collection includes data files of in-cylinder flowvelocity and flame imaging, as well as engine and system geometry needed to set up 1-D and CFD simulations. and README for TCCIII_Collection: https://umich.box.com/v/Collection-README-rev20180202
- Keyword:
- internal combustion engine, TCC III engine, optical engine, CFD validation data, motored engine, turbulence in engines, cyclic variability, laser imaging data, particle image velocimetry, PIV, in-cylinder flow, and OH chemiluminescence
- Citation to related publication:
- http://dx.doi.org/10.2516/ogst/2015028 and http://dx.doi.org/10.1177/1468087417720558
4Works -
S’Urachi Site-Based Archaeological Survey
User Collection
- Creator:
- Gosner, Linda R.
- Description:
- This data was produced by the site-based archaeological survey at the nuraghe S'Urachi in west-central Sardinia (San Vero Milis, Oristano, Sardinia). The survey was carried out from 2015-2017 as a part of the ongoing Progetto S'Urachi, an archaeological project that aims to understand daily life around the monumental Bronze Age tower of S'Urachi during the later occupation of the landscape over the course of the 1st millennium BCE.
- Keyword:
- Mediterranean archaeology, Sardinia, Archaeological Survey, Excavation, and Classical Archaeology
- Discipline:
- Social Sciences
2Works -
Survey Data
User Collection
- Creator:
- Galaty, Michael
- Description:
- All databases, field notebooks, paper maps, GIS files, photographs, and photo descriptions related to the intensive survey, of tracts and tumuli, and the collection of sites have been made available in PASH Deep Blue Data Realm 1. The data are broadly organized by team (A-K). The surveyed land was divided up into “tracts”. Tracts are labeled with team letter and a consecutive number: e.g., A-001, A-002, B-003, C-122, D-035.
- Keyword:
- Archaeology
- Discipline:
- Science
6Works -
Stray Finds
User Collection
- Creator:
- Vani Archaeological Survey
- Description:
- Stray finds documented by the Vani Archaeological Survey
- Keyword:
- Stray Find
5Works