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Filtering by: Creator Amouzandeh, Ghoncheh Creator Chenevert, Thomas L. Creator Gamon, Seth T. Discipline Health Sciences

NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) Diffusion Weighted Imaging Phantom Round Robin

Creator:

Chenevert, Thomas L., Malyarenko, Dariya, Amouzandeh, Ghoncheh, Pickup, Stephen, Zhou, Rong, Manning, Henry Charles, Gamon, Seth T., Shoghi, Kooresh I., Quirk, James D., Sriram, Renuka, Larson, Peder, Lewis, Mickael T., Pautler, Robia G., Kinahan, Paul E., and Muzi, Mark

Description:

Goals of this work quantify repeatability and reproducibility across multiple NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) preclinical MRI systems in performing diffusion measurement using a standardized acquisition protocol on a shared phantom containing temperature-controlled medium of known diffusivity. To achieve these goals, the CIRP Image Acquisition Data Processing (IADP) working group (WG) performed a round-robin study of an ice water-based DWI phantom using a detailed phantom preparation procedure and standardized DWI acquisition protocol, with both site- and core-lab generated ADC measurements derived from shared datasets.

Keyword:

diffusion MRI, pre-clinical MRI, apparent diffusion coefficient (ADC), repeatability, reproducibility, and accuracy

Citation to related publication:

Tomography 2023, 9, 375–386. https://doi.org/10.3390/tomography9010030

Discipline:

Health Sciences