NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) Diffusion Weighted Imaging Phantom Round Robin

Chenevert, Thomas L.; Malyarenko, Dariya; Amouzandeh, Ghoncheh; Pickup, Stephen; Zhou, Rong; Manning, Henry Charles; Gamon, Seth T.; Shoghi, Kooresh I.; Quirk, James D.; Sriram, Renuka; Larson, Peder; Lewis, Mickael T.; Pautler, Robia G.; Kinahan, Paul E.; Muzi, Mark

Work Description

Title: NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) Diffusion Weighted Imaging Phantom Round Robin Open Access Deposited

Attribute	Value
Methodology	A temperature-controlled phantom provided an absolute reference standard to measure apparent diffusion coefficient (ADC) on pre-clinical MRI scanners using standardized procedures. Spatial uniformity of ADC bias and variance were assessed. Seven institutions participated in the study where diffusion weighted imaging (DWI) datasets were acquired over multiple days on 10 pre-clinical scanners, from 3 vendors at 6 field strengths. Centralized versus site-based analysis was also compared to illustrate incremental variance due to processing workflow.
Description	Goals of this work quantify repeatability and reproducibility across multiple NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) preclinical MRI systems in performing diffusion measurement using a standardized acquisition protocol on a shared phantom containing temperature-controlled medium of known diffusivity. To achieve these goals, the CIRP Image Acquisition Data Processing (IADP) working group (WG) performed a round-robin study of an ice water-based DWI phantom using a detailed phantom preparation procedure and standardized DWI acquisition protocol, with both site- and core-lab generated ADC measurements derived from shared datasets.
Creator	Chenevert, Thomas L.; Malyarenko, Dariya; Amouzandeh, Ghoncheh; Pickup, Stephen; Zhou, Rong; Manning, Henry Charles; Gamon, Seth T.; Shoghi, Kooresh I.; Quirk, James D.; Sriram, Renuka; Larson, Peder; Lewis, Mickael T.; Pautler, Robia G.; Kinahan, Paul E.; and Muzi, Mark
Creator ORCID	https://orcid.org/0000-0003-1476-4274
Depositor	tlchenev@umich.edu
Contact information	tlchenev@med.umich.edu
Discipline	Health Sciences
Funding agency	National Institutes of Health (NIH)
ORSP grant number	NIH U24 CA237683
Keyword	diffusion MRI pre-clinical MRI apparent diffusion coefficient (ADC) repeatability reproducibility accuracy
Date coverage	2021-02-23 to 2022-04-11
Citations to related material	Tomography 2023, 9, 375–386. https://doi.org/10.3390/tomography9010030
Related items in Deep Blue Documents	https://hdl.handle.net/2027.42/176134
Resource type	Dataset
Last modified	08/01/2023
Published	08/01/2023
Language	English
DOI	https://doi.org/10.7302/zx39-7s47
License	http://creativecommons.org/licenses/by-nc/4.0/

To Cite this Work:
Chenevert, T. L., Malyarenko, D., Amouzandeh, G., Pickup, S., Zhou, R., Manning, H. C., Gamon, S. T., Shoghi, K. I., Quirk, J. D., Sriram, R., Larson, P., Lewis, M. T., Pautler, R. G., Kinahan, P. E., Muzi, M. (2023). NIH/NCI Co-Clinical Imaging Research Resources Program (CIRP) Diffusion Weighted Imaging Phantom Round Robin [Data set], University of Michigan - Deep Blue Data. https://doi.org/10.7302/zx39-7s47

Relationships


This work is not a member of any user collections.

Files (Count: 5; Size: 1.61 GB)

Title	Original Upload	Last Modified	File Size	Access	Actions
Analysis.zip	2023-04-14	2023-04-14	67.1 MB	Open Access	View Details Download
Code.zip	2023-04-14	2023-04-14	569 KB	Open Access	View Details Download
Products.zip	2023-04-14	2023-04-14	3.17 MB	Open Access	View Details Download
RawData.zip	2023-04-14	2023-04-14	1.54 GB	Open Access	View Details Download
README.docx	2023-04-14	2023-08-01	15.4 KB	Open Access	View Details Download

Download All Files (To download individual files, select them in the “Files” panel above)

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.