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Research data supporting "Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Meta-Iodobenzylguanidine Derivatives for Enhanced Cellular Internalization"

Creator:

Potter, Natalie S., McLean, Alan , Bornowski, Evan C., Hopkins, Thomas, Luo, Jingyi, Wolfe, John P., Qian, Wei, and Kopelman, Raoul

Description:

Research data supporting, 'Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Meta-Iodobenzylguanidine Derivatives for Enhanced Cellular Internalization', 10.1021/acsmaterialslett.3c00781, AuNP = Au nanoparticle. In 10.1021/acsmaterialslett.3c00781, we report the synthesis and application of two metaiodobenzylguanidine (MIBG) derivatives decorated on the surface of AuNPs at high molar ratios; greatly enhanced cellular uptake is observed across neuroblastoma (NB), HeLa, and HEK cell lines. This dataset consists of synthetic NMR and mass spec data for the small molecules and their intermediates, dark-field microscopy data, inductively-coupled plasma mass spectrometry data, and raw data for characterizing the AuNPs (TEM, DLS, zeta potential).

Keyword:

chemistry, MIBG, nanoparticle, AuNP, synthesis, ICP-MS

Citation to related publication:

Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Metaiodobenzylguanidine Derivatives for Enhanced Cellular Internalization Natalie S. Potter, Alan McLean, Evan C. Bornowski, Thomas Hopkins, Jingyi Luo, John P. Wolfe, Wei Qian, and Raoul Kopelman ACS Materials Letters Article ASAP DOI: 10.1021/acsmaterialslett.3c00781

Discipline:

Science

Research data supporting "Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Meta-Iodobenzylguanidine Derivatives for Enhanced Cellular Internalization"

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Research data supporting "Flexible Synthesis Scheme and Application of AuNP Surface-Conjugatable Meta-Iodobenzylguanidine Derivatives for Enhanced Cellular Internalization"

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