Now showing items 391-400 of 444
Automated integration of monolith-based protein separation with on-plate digestion for mass spectrometric analysis of esophageal adenocarcinoma human epithelial samples
(WILEY-VCH Verlag, 2006-09)
A unique approach of automating the integration of monolithic capillary HPLC-based protein separation and on-plate digestion for subsequent MALDI-MS analysis has been developed. All liquid-handling procedures were performed ...
The Interdisciplinary Biophysics Graduate Program at the University of Michigan
(Wiley Subscription Services, Inc., A Wiley Company, 2008-04)
The Michigan Biophysics Graduate Program (MBGP) was established in 1949, making it one of the first such programs in the world. The intellectual base of the program was significantly broadened in the 1980 when faculty ...
Molybdenum carbide catalysts for water–gas shift
(Kluwer Academic Publishers-Plenum Publishers; Kluwer Academic Publishers ; Springer Science+Business Media, 2000-12)
Molybdenum carbide (Mo 2 C) was demonstrated to be highly active for the water–gas shift of a synthetic steam reformer exhaust stream. This catalyst was more active than a commercial Cu–Zn–Al shift catalyst under the ...
Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry
(Wiley Periodicals, Inc., 2000-02)
Because of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is ...
Selection for Catalytic Function with Nucleic Acids
(Wiley Periodicals, Inc.Cold Spring Harbor, 2000-02)
For in vitro selection of catalytic polynucleotides, each new protocol must be designed to harness the desired catalytic activity to help propel the selection process itself. This unit gives guidelines for design of in ...
A Metal–Organic Framework with a Hierarchical System of Pores and Tetrahedral Building Blocks
(WILEY-VCH Verlag, 2006-04-10)
No Abstract
Attachment of Reporter and Conjugate Groups to the 3′ Termini of Oligonucleotides
(Wiley Periodicals, Inc.Humana Press, 2000-10)
Conjugation of oligonucleotides at the 3 terminus is less common because this site is used for covalent linkage to solid‐phase oligonucleotide synthesis supports. However, 3‐oligonucleotide conjugates have several valuable ...
Recent Advances in RNA Structure Determination by NMR
(John Wiley & Sons, 2000-10)
Despite recent advances in the solution of NMR structures of RNA and RNA‐ligand complexes, the rate limiting step remains the gathering of a large number of NOE and torsion restraints. Additional sources of information for ...
A self-renewal assay for cancer stem cells
(Springer-Verlag, 2005-11)
Cancers of epithelial origin are responsible for the majority of cancer-related deaths in the USA. Unfortunately, although chemotherapy and/or radiation therapy can sometimes shrink tumors, metastatic cancers of epithelial ...
In the fluorescent spotlight: Global and local conformational changes of small catalytic RNAs
(Wiley Subscription Services, Inc., A Wiley Company, 2002)
RNA is a ubiquitous biopolymer that performs a multitude of essential cellular functions involving the maintenance, transfer, and processing of genetic information. RNA is unique in that it can carry both genetic information ...