Now showing items 31-40 of 1108
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53
(John Wiley & Sons, Ltd, 2007-11-28)
Time course of tinnitus development following noise exposure in mice
(Wiley Subscription Services, Inc., A Wiley Company, 2012-07)
Gap‐induced prepulse inhibition of acoustic startle (GPIAS) has been used in rats and mice to study the problem of tinnitus. The current study demonstrates that similar methods can be used to study the temporal development ...
Effects of hydroxyurea on CNV induction in the mouse germline
(John Wiley & Sons, Inc., 2018-10)
More TORC for the gluconeogenic engine
(Wiley Subscription Services, Inc., A Wiley Company, 2006-03)
Hepatic gluconeogenesis plays a key role in the maintenance of glucose homeostasis. The hormone glucagon stimulates this process, whereas insulin and adiponectin are inhibitory. In a recent report, Koo et al identify the ...
Rareâ variant association tests in longitudinal studies, with an application to the Multiâ Ethnic Study of Atherosclerosis (MESA)
(Wiley Periodicals, Inc.Springer New York, 2017-12)
Over the past few years, an increasing number of studies have identified rare variants that contribute to trait heritability. Due to the extreme rarity of some individual variants, geneâ based association tests have been ...
Early events of Bacillus anthracis germination identified by time-course quantitative proteomics
(WILEY-VCH Verlag, 2006-10)
Germination of Bacillus anthracis spores involves rehydration of the spore interior and rapid degradation of several of the protective layers, including the spore coat. Here, we examine the temporal changes that occur ...
Electron detachment dissociation of fluorescently labeled sialylated oligosaccharides
(WILEY‐VCH Verlag, 2011-12)
We explored the application of electron detachment dissociation (EDD) and infrared multiphoton dissociation (IRMPD) tandem mass spectrometry to fluorescently labeled sialylated oligosaccharides. Standard sialylated ...
Modulation of cAMP levels by highâ fat diet and curcumin and regulatory effects on CD36/FAT scavenger receptor/fatty acids transporter gene expression
(Wiley Periodicals, Inc., 2017-01-02)
Curcumin, a polyphenol from turmeric (Curcuma longa), reduces inflammation, atherosclerosis, and obesity in several animal studies. In Ldlrâ /â mice fed a highâ fat diet (HFD), curcumin reduces plasma lipid levels, ...
Visualization of Protein Interactions in Living Cells Using Bimolecular Fluorescence Complementation (BiFC) Analysis
(Wiley Periodicals, Inc., 2005-12)
Protein interactions integrate stimuli from different signaling pathways and developmental programs. Bimolecular fluorescence complementation (BiFC) analysis has been developed for visualization of protein interactions in ...
Use of inverse PCR to amplify and sequence breakpoints of HPRT deletion and translocation mutations
(John Wiley & Sons, Inc., 2002)
Deletion and translocation mutations have been shown to play a significant role in the genesis of many cancers. The hprt gene located at Xq26 is a frequently used marker gene in human mutational studies. In an attempt ...