Now showing items 3351-3360 of 3410
Gestational diabetes mellitus, epigenetic age and offspring metabolism
(Wiley Periodicals, Inc., 2022-11)
AimsNo reports examine the relationship between in-utero exposure to gestational diabetes mellitus (GDM), offspring epigenetic age acceleration (EAA), and offspring insulin sensitivity.MethodsUsing data from a cohort study, ...
Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR)
(Wiley Periodicals, Inc., 2022-11)
Children with relapse of T-cell acute lymphoblastic leukemia (T-ALL) or lymphoblastic lymphoma (T-LBL) have a dismal prognosis, largely due to difficulty attaining second remission. We hypothesized that adding etoposide ...
Delayed urologic cancer care in the COVID-19 pandemic: Patients’ experiences
(Wiley Periodicals, Inc., 2022-11)
ObjectiveTo understand experiences of patients with genitourinary cancer who experienced delayed cancer care due to the COVID-19 pandemic.MethodsWe conducted a mixed methods study with an explanatory sequential design. ...
Repeat-Associated Non-AUG Translation of AGAGGG Repeats that Cause X-Linked Dystonia-Parkinsonism
(John Wiley & Sons, Inc., 2022-11)
BackgroundX-linked dystonia-parkinsonism (XDP) is a neurodegenerative disorder caused by the intronic insertion of a SINE-VNTR-Alu (SVA) retrotransposon carrying an (AGAGGG)n repeat expansion in the TAF1 gene. The molecular ...
Advanced MRI to differentiate schwannomas and metastases in the cerebellopontine angle/internal auditory canal
(Wiley Periodicals, Inc., 2022-11)
Background and PurposeDifferentiating schwannomas and metastases in the cerebellopontine angles (CPA)/internal auditory canals (IAC) can be challenging. This study aimed to assess the role of diffusion-weighted imaging ...
Guardianship: A medicolegal review for clinicians
(John Wiley & Sons, Inc., 2022-11)
Guardianship may pose an ethical dilemma for physicians, who must balance protecting vulnerable patients from potential safety concerns with respecting their autonomy. Older adults with dementia are particularly susceptible ...
Summary and conclusions, and abbreviations and acronyms
(Wiley Periodicals, Inc., 2022-12)
Pronounced squamous cell contamination in biliary tract cytology: A diagnostic pitfall
(John Wiley & Sons, Inc., 2022-11)
Squamous cells are rarely found in biliary tract cytology specimens, and when present are typically scant in quantity. Over an 8-year time period, two cases at our institution reporting abundant squamous cells were identified. ...
The Role of Mechanosensitive Calcium Signaling in Remodeling of Epithelial Cell-Cell Junctions
(2021)
Epithelial cells line most of our body cavities, separating different compartments in our bodies, creating selective barriers, and protecting us from external pathogens. In epithelial tissues, cells experience a range of ...
Mechanisms and Consequences of GLO1 Attenuation in Obese Skeletal Muscle: Exploring a Potential Role for SIRT1-Mediated GLO1 Stability
(2022)
The obesity pandemic is persistent with global rates of obesity exceeding 13%. Obesity results in the development of insulin resistance which through a myriad of mechanisms increases the risk for secondary disease development ...