Now showing items 11-20 of 369
Dynamic competition between a ligand and transcription factor NusA governs riboswitch-mediated transcription regulation
(2021-10-14)
Co-transcriptional RNA folding is widely assumed to influence the timely control of gene expression, but our understanding remains limited. In bacteria, the fluoride (F-) sensing riboswitch is a transcriptional control ...
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Development of High Energy Density Diaminocyclopropenium‐Phenothiazine Hybrid Catholytes for Non‐Aqueous Redox Flow Batteries
(Wiley Periodicals, Inc., 2021-12-20)
This report describes the design of diaminocyclopropenium‐phenothiazine hybrid catholytes for non‐aqueous redox flow batteries. The molecules are synthesized in a rapid and modular fashion by appending a diaminocyclopropenium ...
Lanthanide Identity Governs Guest‐Induced Dimerization in LnIII[15‐MCCuIIN(L‐pheHA)‐5])3+ Metallacrowns
(John Wiley & Sons, Inc., 2021-12-15)
Series of lanthanide‐containing metallic coordination complexes are frequently presented as structurally analogous, due to the similar chemical and coordinative properties of the lanthanides. In the case of chiral ...
Triggered Reversible Disassembly of an Engineered Protein Nanocage**
(Wiley Periodicals, Inc., 2021-11-15)
Protein nanocages play crucial roles in sub- cellular compartmentalization and spatial control in all domains of life and have been used as biomolecular tools for applications in biocatalysis, drug delivery, and ...
Mixed‐solvent molecular dynamics simulation‐based discovery of a putative allosteric site on regulator of G protein signaling 4
(John Wiley & Sons, Inc., 2021-11-15)
Regulator of G protein signaling 4 (RGS4) is an intracellular protein that binds to the Gα subunit ofheterotrimeric G proteins and aids in terminating G protein coupled receptor signaling. RGS4 has been implicated in pain, ...
Reformulating the permselectivity‐conductivity tradeoff relation in ion‐exchange membranes
(John Wiley & Sons, Inc., 2021-11-01)
Polymer membranes used in separation applications exhibit a tradeoff between permeability and selectivity. That is, membranes that are highly permeable tend to have low selectivity and vice versa. For ion‐exchange membranes ...
The structure of natively iodinated bovine thyroglobulin
(International Union of CrystallographyWiley Periodicals, Inc., 2021-11-01)
An improved Poisson‐Nernst‐Planck ion channel model and numerical studies on effects of boundary conditions, membrane charges, and bulk concentrations
(John Wiley & Sons, Inc., 2021-10-15)
In this paper, an improved Poisson‐Nernst‐Planck ion channel (PNPic) model is presented, along with its effective finite element solver and software package for an ion channel protein in a solution of multiple ionic species. ...
Stereoselective β‐Mannosylation via Anomeric O‐Alkylation with L‐Sugar‐Derived Electrophiles
(Wiley Periodicals, Inc., 2021-12-28)
A total synthesis of the trisaccharide repeat unit of Salmonella serogroup E1 O‐antigen is reported. This synthesis features a key β‐mannosylation reaction through a cesium carbonate‐mediated anomeric O‐alkylation of a ...