Now showing items 3851-3860 of 3872
Identification of regulatory variants of carboxylesterase 1 (CES1): A proof-of-concept study for the application of the Allele-Specific Protein Expression (ASPE) assay in identifying cis-acting regulatory genetic polymorphisms
(Wiley Periodicals, Inc., 2023-01)
It is challenging to study regulatory genetic variants as gene expression is affected by both genetic polymorphisms and non-genetic regulators. The mRNA allele-specific expression (ASE) assay has been increasingly used for ...
Chromatography and Anti-Biofilm Activity of Chiral Carbon Nanoparticles
(2023)
Biofilms have evolved to be resistant to natural and man-made antibiotics. The biochemical composition and barrier function of the extracellular polymeric substance prevent penetration of traditional antimicrobials reduce ...
Understanding the Aqueous-Phase Adsorption and Hydrogenation of Model Bio-Oil Molecules on Metals and Alloys
(2023)
Valorization of biomass-derived molecules via aqueous-phase catalytic hydrogenation is a promising strategy for producing CO2-neutral fuels and chemicals to reduce our reliance on fossil fuels and lower our greenhouse gas ...
Sustainable decision making for chemical process systems via dimensionality reduction of many objective problems
(John Wiley & Sons, Inc., 2023-02)
Recent global events and the rise of sustainable investing have made clear that the chemical and energy industry must consider sustainability goals beyond profit maximization to remain competitive. Multiobjective optimization ...
Investigating Aqueous-Phase Adsorption for Enhancing (Electro)catalytic Hydrogenation
(2023)
Bio-oil derived from biomass and plastic wastes is a promising substitute to traditional petroleum for use as transportation fuels and chemical precursors and as such it has the potential to combat global warming. However, ...
Engineering Protein-Drug Conjugates for Solid Tumor Immunotherapy
(2022)
Antibody therapies have dominated biologics for many years. The innate specificity and long half-lives of these proteins provide a sustained response in many disease indications, including cancer. However, solid tumors can ...
A Bidentate Ligand Featuring Ditopic Lewis Acids in the Second Sphere for Selective Substrate Capture and Activation
(Wiley Periodicals, Inc., 2023-03-20)
We present a ligand platform featuring appended ditopic Lewis acids to facilitate capture/activation of diatomic substrates. We show that incorporation of two 9-borabicyclo[3.3.1]nonane (9-BBN) units on a single carbon ...
Engineering the Flow of Energy and Charge Carriers in Hybrid Plasmonic Systems and Catalysts
(2022)
The emission of greenhouse gases due to the combustion of fossil fuels (i.e., coal, oil, and natural gas) is unanimously recognized as the primary driver of climate change. One attractive option for shifting away from a ...
Scalable Networks of Engineered Extracellular Matrix as Biomimetic Tissue Culture Models with Defined Heterogeneity
(2021)
The extracellular matrix (ECM) is a complex amalgam of proteins and polysaccharides that actively influences cell fate via biochemical and biophysical cues. Fibronectin (Fn) is the bedrock of many native interstitial ECM, ...
Revolutionizing Energetic Materials Discovery and Design: The Role of Data Science and Machine Learning
(Wiley Periodicals, Inc., 2023-03)