Now showing items 21-30 of 729
Streptococcus faecalis sex pheromone (cAD1) response: Evidence that the peptide inhibitor excreted by pAD1-containing cells may be plasmid determined
(Elsevier, 1987-01)
Streptococcus faecalis strains harboring the conjugative plasmid pAD1 excrete a small peptide, iAD1, which inhibits the sex pheromone cAD1. Studies making use of the host strain Streptococcus faecium 9790, which normally ...
Rareâ variant association tests in longitudinal studies, with an application to the Multiâ Ethnic Study of Atherosclerosis (MESA)
(Wiley Periodicals, Inc.Springer New York, 2017-12)
Over the past few years, an increasing number of studies have identified rare variants that contribute to trait heritability. Due to the extreme rarity of some individual variants, geneâ based association tests have been ...
Sister-chromatid exchange and chromosome aberrations for 4 aliphatic epoxides in mice
(Elsevier, 1989-10)
Sister-chromatid exchange (SCE) and chromosome aberrations (CA) in bone marrow cells were analyzed after in vivo exposure in mice to 4 aliphatic epoxides, namely 1-naphthyl glycidyl ether (NGE), 1-naphthyl propylene oxide ...
Use of inverse PCR to amplify and sequence breakpoints of HPRT deletion and translocation mutations
(John Wiley & Sons, Inc., 2002)
Deletion and translocation mutations have been shown to play a significant role in the genesis of many cancers. The hprt gene located at Xq26 is a frequently used marker gene in human mutational studies. In an attempt ...
Heteroplasmy of chloroplast DNA in Medicago
(Kluwer Academic Publishers; Springer Science+Business Media, 1989-01)
Two chloroplast DNA (cpDNA) regions exhibiting a high frequency of intra- or inter-species variation were identified in 12 accessions of the genus Medicago . Restriction maps of both regions were prepared for alfalfa, and ...
Macromolecular organization and genetic mapping of a rapidly evolving chromosome-specific tandem repeat family (B77) in cotton (Gossypium)
(Kluwer Academic Publishers; Springer Science+Business Media, 1998-12)
Isolation and characterization of the most prominent repetitive element families in the genome of tetraploid cotton (Gossypium barbadense L; [39]) revealed a small subset of families that showed very different properties ...
Post-meiotic transcription in mouse testes detected with spermatid cDNA clones
(Kluwer Academic Publishers; The Biochemical Society ; Springer Science+Business Media, 1984-12)
cDNA clones to poly(A) + mRNA from spermatids have been obtained to study gene transcription in post-meiotic germ cells. Four cDNA clones detect mRNAs that increase in abundance in post-meiotic germ cells. One clone, pPM459, ...
The Role of Environmental Heterogeneity in Meta‐Analysis of Gene–Environment Interactions With Quantitative Traits
(Wiley, 2014-07)
With challenges in data harmonization and environmental heterogeneity across various data sources, meta‐analysis of gene–environment interaction studies can often involve subtle statistical issues. In this paper, we study ...
Heterozygosity and ethnic variation in Japanese platelet proteins
(Springer-Verlag, 1988-01)
Sixty-two polypeptides visualized on silver-stained two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) preparations of platelets from 85 Japanese subjects, in total 5,252 spots, have been scored for genetic ...
Copy number variant discrepancy resolution using the ClinGen dosage sensitivity map results in updated clinical interpretations in ClinVar
(Wiley Periodicals, Inc., 2018-11)
Conflict resolution in genomic variant interpretation is a critical step toward improving patient care. Evaluating interpretation discrepancies in copy number variants (CNVs) typically involves assessing overlapping genomic ...