Now showing items 1221-1230 of 1236
The Anti‐G0 Manifesto: Should a problematic construct (G0) with no biological reality be removed from the cell cycle? Yes!
(Wiley Periodicals, Inc., 2021-03)
It is widely accepted that there exists a “resting” or “quiescent” state where a growing cell leaves the cell cycle to enter what is often called the “G0‐phase.” I propose that there is no biological reality to the “G0‐phase.” ...
CFTR Does Not Alter Acidification of L Cell Endosomes
(Elsevier, 1994-11-30)
Endosomes from L cells, transduced with the CFTR gene, and the parental line, which does not express detectable levels of CFTR, were loaded with FITC-dextran, isolated and the initial rates of acidification, steady-state ...
Disparate gene expression of chemotactic cytokines by human mononuclear phagocytes
(Elsevier, 1990-01-30)
Chemotactic cytokines are becoming increasingly recognized as important participants in the coordinate recruitment of specific inflammatory cells. In this manuscript we present data demonstrating that LPS challenged human ...
Soil respiration in northern forests exposed to elevated atmospheric carbon dioxide and ozone
(Springer-Verlag, 2006-02-18)
The aspen free-air CO 2 and O 3 enrichment (FACTS II–FACE) study in Rhinelander, Wisconsin, USA, is designed to understand the mechanisms by which young northern deciduous forest ecosystems respond to elevated atmospheric ...
Microclimatic changes and the indirect loss of ant diversity in a tropical agroecosystem
(Springer-Verlag, 1996-11)
Recent changes in the coffee agroecosystem of Costa Rica were used to study the mechanism of biodiversity loss in transforming agroecosystems, focusing on the ground-foraging ant community. Coffee farms are being transformed ...
Bone regeneration via skeletal cell lineage plasticity: All hands mobilized for emergencies
(Wiley Periodicals, Inc., 2021-01)
An emerging concept is that quiescent mature skeletal cells provide an important cellular source for bone regeneration. It has long been considered that a small number of resident skeletal stem cells are solely responsible ...
Elucidating the Genetic Basis of Pigmentation Differences between Drosophila Species.
(2012)
Understanding how phenotypes change has been a long-standing question in evolutionary biology. The research presented here investigates the genetic basis of the pigmentation difference exhibited between the dark pigmented ...
Patched Together: cis-Regulatory Logic of the Hedgehog Response.
(2016)
Understanding the processes that control how we develop from a fertilized embryo to a functional adult is paramount for treating the diseases that result when these processes are disrupted at any stage of life. My dissertation ...
Inside or Out: Characterizing petrobactin use by Bacillus anthracis
(2018)
Bacillus anthracis is a Gram-positive, spore-forming bacillus and causes the disease anthrax. Anthrax is a deadly infection that begins with phagocytosis of a B. anthracis spore by an antigen presenting cell and ends when ...
Molecular Investigation of Human-Specific Neurobiology: From Cortical Evolution to Neurodevelopmental Disorders
(2022)
The human brain evolves under a unique set of adaptive pressures, distinguishing aspects of form and function from the brains of other primate species. An outstanding question in evolutionary biology is the biological ...