Now showing items 21-30 of 152
Interaction of viable group a streptococci and hydrogen peroxide in killing of vascular endothelial cells
(Elsevier, 1993-05)
Previous studies have shown that the streptococcal hemolysin, streptolysin S, is capable of interacting with hydrogen peroxide (H2O2) to injure vascular endothelial cells (Free Radic. Biol. Med. 7:369-376; 1989). To extend ...
The synthesis of DL-3,3-Difluoroglutamic acid from a 3-oxoprolinol derivative
(Elsevier, 1993-07-30)
DL-3,3-Difluoroglutamic acid was synthesized from a masked 3-hydroxyprolinol, 6-hydroxy-1-aza-3-oxabicyclo[3.3.0]octan-2-one, in eight steps. The described synthetic route expands the utility of fluoroproline derivatives ...
Evidence that macrophages are programmed to die after activating autologous, cloned, antigen-specific, CD4 + T cells
(WILEY-VCH Verlag GmbH, 1993-07)
The bone marrow produces large numbers of monocytes daily, but the mechanisms balancing production and elimination are unknown. In this report we demonstrate that macrophages (Mφ) undergo apoptosis after activating autologous ...
The gustatory competence of the lingual epithelium requires neonatal innervation
(Elsevier, 1993-04-16)
The rat vallate papilla is bilaterally innervated by the IXth nerve whose axons are required for the normal development of its several hundred taste buds. Temporary denervation during the developmental sensitive period for ...
The Α-mannosyl-binding lectin from leaves of the orchid twayblade ( Listera ovata )
(Blackwell Publishing Ltd, 1993-10)
Assay of human plasma cortisone by liquid chromatography: normal plasma concentrations (between 8 and 10 a.m.) of cortisone and corticosterone
(Elsevier, 1993-04-02)
A high-performance liquid chromatographic method using ultraviolet detection to quantitate human plasma concentrations of cortisone simultaneously with cortisol and corticosterone is described. The method is based on the ...
A Continuous Spectrophotometric and Fluorometric Assay for Protein Tyrosine Phosphatase Using Phosphotyrosine-Containing Peptides
(Elsevier, 1993-05-15)
Two continuous assays for protein tyrosine phosphatases (PTPases) have been developed using phosphotyrosine containing peptide substrates. These assays are based on the marked differences in the spectra of the peptide ...
Molecular Characterization of the Murine Neural Retina Leucine Zipper Gene, Nrl
(Elsevier, 1993-11)
The NRL gene (D14S46E) is expressed in cells of human retina and encodes a putative DNA-binding protein of the leucine zipper family. Here we describe the analysis of the murine homolog of the NRL gene, Nrl. Various cDNAs ...
IGF receptor function and regulation in autocrine human neuroblastoma cell growth
(Elsevier, 1993-10-20)
Insulin-like growth factor-II (IGF-II) and its receptors (type I and II IGF receptors) are expressed in the nervous system in a tissue and developmentally specific manner. We have previously shown that SH-SY5Y human ...
Inhibitors of thymidylate synthase and dihydrofolate reductase potentiate the antiviral effect of acyclovir
(Elsevier, 1993-03)
In cells infected with herpes simplex virus type 1, intracellular dNTP pools increased markedly. Treatment of these cells with 3 [mu]M acyclovir resulted in an additional expansion in pyrimidine deoxyribonucleoside ...