Now showing items 4661-4670 of 4795
High-Resolution Mapping of Genome Position Expression Variation in Bacteria & Engineering of Microbial Consortia for Cellulosic Biochemical Production
(2018)
High-resolution mapping of genome position expression variation in bacteria: To elucidate the effect of position in the bacterial genome on gene expression at a high resolution, we have developed a multiplex strategy to ...
Role of Histone Methyltransferase SET-4 in Developmental Plasticity and Longevity
(2017)
FoxO transcription factors promote longevity across diverse organisms through upregulation of
parallel stress responses. Therefore, understanding how FoxO activity is regulated may provide
insights for improving overall ...
Uncovering Reproductive Roles Of Cell Wall Glycoproteins In Flowering Plants
(2022)
Plant cells are surrounded by a polysaccharide-rich extracellular matrix, the cell wall. The cell wall constitutes the interphase of interaction between the cell and its surrounding environment, as well as a medium for ...
A Robust and Tunable Mitotic Oscillator in Artificial Cells
(2018)
This dissertation aims to develop a droplet-based artificial cell system using cell-free extracts of Xenopus laevis eggs and understand mitotic oscillations with the proposed system. Single-cell analysis is pivotal to ...
Elucidating the Role of GRASPs In and Out of the Golgi Apparatus
(2021)
The stacking of flattened cisternae is the basic structure of the Golgi apparatus. In mammalian cells, these stacks are linked into a ribbon-like structure located at the perinuclear region of the cell. It has been previously ...
Characterization of Caytaxin Protein in Animal Models of Cerebellar Dysfunction.
(2012)
Over 150,000 Americans have been diagnosed with ataxia, however most are untreatable due to yet-unknown etiologies. The work described within this dissertation aims to expand current knowledge regarding ataxia and the brain ...
Cancer-Stem-Cell-Like, Wnt/TCF Responsive Cells Are Activated by Pax8 PPAR? Fusion Protein.
(2013)
Pax8 PPARγ Fusion Protein (PPFP) occurs in ~35% of follicular thyroid carcinoma cases. Expression of PPFP in the non-transformed rat thyroid cell line PCCL3 conferred on the cells the ability to invade through matrigel and ...
Investigating Cell Cycle Re-entry in the Drosophila brain: From the Pupa to the Adult
(2020)
G0 associated with terminal differentiation represents the most common cellular state in adult multicellular organisms, yet it is poorly understood. In past years, various tissues of the fruit fly Drosophila melanogaster ...
The HERV-K Np9 Protein Regulates Viability of Teratocarcinoma Cells
(2019)
Human endogenous retroviruses are remnants of ancient germline infections that make up approximately 8% of the modern human genome. Most HERVs entered primates approximately 40 million years ago, and have been rendered ...
A WUSCHEL-Independent Stem Cell Specification Pathway is Repressed by PHB, PHV and CNA in Arabidopsis.
(2014)
A tight balance between stem cell specification and differentiation is important to maintain a functional meristem and continuously initiate new organs throughout the lifespan of plants. The Arabidopsis WUSCHEL (WUS) ...