Now showing items 1-10 of 12
Designing Thermal Modulators for Portable GC x GC Systems.
(2015)
Microelectromechanical systems (MEMS) have the advantage of scale and can be manufactured in bulk. One of the active areas of MEMS research is the development of micro-scale comprehensive two-dimensional gas chromatography ...
Methodological Advances for Drug Discovery and Protein Engineering
(2018)
Designing and engineering molecules that have specified properties not only test our understanding of nature but also play an important role in improving both human health and industrial productivity. Two such examples are ...
Quantum Inspired Machine Learning Algorithms for Adaptive Radiotherapy
(2021)
Adaptive radiotherapy (ART) refers to the modification of radiotherapy treatment plans in response to patient anatomical and physiological changes over the course of treatment and has been recognized as an important step ...
Local to Global Multi-Scale Multimedia Modeling of Chemical Fate and Population Exposure
(2017)
To assess environmental and human exposure to chemical emissions, two types of approaches are available: 1. intermediate- to high-resolution, substance/location-specific analyses, and 2. lower resolution, less specific ...
Acoustically-Responsive Scaffolds: Control of Growth Factor Release for Tissue Regeneration Using Ultrasound
(2017)
Administration of exogenous growth factors (GFs) is a proposed method of stimulating tissue regeneration. Conventional administration routes, such as at-site or systemic injections, have yielded problems with efficacy ...
Modeling Dose-Function Response and Toxicity Pathways in Non-Small Cell Lung Cancer Patients Undergoing Radiation Treatment
(2021)
Radiotherapy is currently the standard of care for treating NSCLC patients, and while technological advancements in the field continue to improve our ability to successfully treat these patients, serious side-effects, i.e. ...
Multidisciplinary Study of Soft Shape Morphing Systems
(2021)
Nature abounds with examples of shape morphing systems where an entity either gradually grows into a complex 3-D shape pattern or rapidly morphs into a new configuration. Inspired by the shape shifting capabilities of ...
Advances in Quantitative MRI: Acquisition, Estimation, and Application
(2018)
Quantitative magnetic resonance imaging (QMRI) produces images of potential MR biomarkers: measurable tissue properties related to physiological processes that characterize the onset and progression of specific disorders. ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization.
(2010)
The goal of targeted drug delivery is the spatial and temporal localization of a therapeutic agent and its associated bioeffects. One method of drug localization is acoustic droplet vaporization (ADV), whereby drug-laden ...