Now showing items 7091-7100 of 7121
A multivariate parametric empirical Bayes screening approach for early detection of hepatocellular carcinoma using multiple longitudinal biomarkers
(SpringerWiley Periodicals, Inc., 2022-06-15)
Split and combine simulation extrapolation algorithm to correct geocoding coarsening of built environment exposures
(North American Association of Central Cancer RegistriesWiley Periodicals, Inc., 2022-05-20)
Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium
(John Wiley & Sons, Inc., 2022-05)
Survival outcomes for relapsed/refractory pediatric acute myeloid leukemia (R/R AML) remain dismal. Epigenetic changes can result in gene expression alterations which are thought to contribute to both leukemogenesis and ...
Extending the Continual Reassessment Method to accommodate step‐up dosing in Phase I trials
(Wiley Periodicals, Inc., 2022-09-10)
A Solid Alkylation: Highly Recyclable, Flow Chemistry-Ready, Resin-Supported Thioimidazoliums Alkylate Sulfur-Centered Nucleophiles
(National Institute of Advanced Industrial ScienceWiley Periodicals, Inc., 2022-09-20)
A series of readily regenerable thioimidazolium-based ionic liquids, which can transfer alkyl groups to nucleophiles, are immobilized on crosslinked polystyrene beads. Different alkyl groups can be loaded onto the resin, ...
Dual‐detection approach for a charge variant analysis of monoclonal antibody combination products using imaged capillary isoelectric focusing
(Wiley Periodicals, Inc.Springer Science+Business Media, 2022-09)
The clinical benefits of treatments with a combination of two or more therapeutic monoclonal antibodies (mAbs) have emerged in recent years. Imaged capillary isoelectric focusing is a frequently used technology in the ...
The Total Synthesis of Glycolipids from Streptococcus pneumoniae and a Re-evaluation of Their Immunological Activity**
(ElsevierWiley Periodicals, Inc., 2022-09-16)
Invariant natural killer (iNK) T cells, Type I iNKTs, are responsible for the production of pro-inflammatory cytokines which induce a systemic immune response. They are distinctive in possessing an semi-invariant T-cell ...
Improving large-scale estimation and inference for profiling health care providers
(Massachusetts Medical SocietyWiley Periodicals, Inc., 2022-07-10)
Provider profiling has been recognized as a useful tool in monitoring health care quality, facilitating inter-provider care coordination, and improving medical cost-effectiveness. Existing methods often use generalized ...
Semiparametric analysis of a generalized linear model with multiple covariates subject to detection limits
(John Wiley & Sons, Inc., 2022-10-30)