Now showing items 21-30 of 94
Anatomical relationship between opioid peptides and receptors in rhesus monkey brain
(Elsevier, 1984-12)
To determine whether opioid peptide-receptor pharmacological associations found in vitro (e.g., enkephalin-[delta], dynorphin-[kappa]) predict anatomical relationships in situ, immunocytochemical and receptor autoradiographic ...
Degradation of [3H][beta]-endorphin in rat plasma is increased with chronic stress
(Elsevier, 1989-08-22)
With a number of acute stressors [beta]-endorphin is released into plasma. It is unclear if [beta]-endorphin is converted into any other biologically active products, nor it is clear if the rate or pathways of degradation ...
Pulse-chase studies of the POMC/Beta-endorphin system in the pituitary of acutely and chronically stressed rats
(Elsevier, 2006-04-07)
Experiments were carried out to determine whether stress induces biochemical changes in the pro-opiomelanocortin (POMC) system in anterior (AL) and intermediate-posterior lobe (IPL) of rat. In a series of pulse-chase ...
Inhibition of opiate tolerance by non-competitive receptor antagonists
(Elsevier, 1994-01-07)
Our laboratory and others have previously reported that the non-competitive (NMDA) receptor antagonist, MK-801, interferes with the development of tolerance to the analgesic effects of morphine. The present studies were ...
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques
(Elsevier, 1992-02)
D1, a subtype of the dopamine receptors, is widely distributed in the nervous system and has been shown to be positively coupled to adenylate cyclase. Using a combination of in vitro receptor autoradiographic and in situ ...
Anatomy of CNS opioid receptors
(Elsevier, 1988)
There is a wide body of evidence to suggest the existence of at least three distinct opioid receptor types in the CNS, referred to as [mu], [delta], and [kappa]. This paper reviews some of the findings that have led to ...
The preferential release of beta-endorphin from the anterior pituitary lobe by Corticotropin Releasing Factor (CRF)
(Elsevier, 1986)
Although a number of investigators have shown that release of ACTH is accompanied by the release of Beta-endorphin ([beta]-End) and Beta-lipotropin ([beta]-LPH), the proportion of the latter two peptides released with ...
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey
(Elsevier, 1985)
Analysis of an acid extract of the striatum of the rhesus monkey revealed that the molar ratio of dynorphin A(1-8)-sized material and dynorphin (A(1-17)-sized material is approximately 1:1. In addition, the molar ratios ...
Some of the [alpha]-NH2-acetylated [beta]-endoprhin-like material in rat and monkey pituitary and brain is acetylated [alpha]- and [beta]-endorphin
(Elsevier, 1983)
There are several studies demonstrating the existence of [alpha]-NH2-acetylated (N-Ac) forms of [beta]-endorphin in the intermediate lobe of several species (1,4,6). These include N-Ac-[beta]-endorphin(1-31), N-Ac-[beta] ...