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Inhibitors of RecA activity discovered by high-throughput screening: cell-permeable small molecules attenuate the SOS response in Escherichia coli.

Wigle, TJ; Sexton, JZ; Gromova, AV; Hadimani, MB; Hughes, MA; Smith, GR; Yeh, LA; Singleton, SF (Elsevier, 2009-01)

(689.6KB)

N-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed mice

Bhagat, HA; Compton, SA; Musso, DL; Laudeman, CP; Jackson, KMP; Yi, NY; Nierobisz, LS; Forsberg, L; Brenman, JE; Sexton, JZ (Public Library of Science (PLoS), 2018-10-01)

(3.5MB)

The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts

Vohnoutka, RB; Gulvady, AC; Goreczny, G; Alpha, K; Handelman, SK; Sexton, JZ; Turnera, CE (American Society for Cell Biology (ASCB), 2019-12-01)

(7.9MB)

Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells

Kalinin, AA; Hou, X; Ade, AS; Fon, GV; Meixner, W; Higgins, GA; Sexton, JZ; Wan, X; Dinov, ID; O'Meara, MJ; Athey, BD (American Society for Cell Biology (ASCB), 2021-08-19)

(1.7MB)

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19

Mirabelli, C; Wotring, JW; Zhang, CJ; McCarty, SM; Fursmidt, R; Pretto, CD; Qiao, Y; Zhang, Y; Frum, T; Kadambi, NS; Amin, AT; O’Meara, TR; Spence, JR; Huang, J; Alysandratos, KD; Kotton, DN; Handelman, SK; Wobus, CE; Weatherwax, KJ; Mashour, GA; O’Meara, MJ; Chinnaiyan, AM; Sexton, JZ (Proceedings of the National Academy of Sciences, 2021-09-07)

(2.6MB)

Gene-Guided Discovery and Ribosomal Biosynthesis of Moroidin Peptides.

Kersten, RD; Mydy, LS; Fallon, TR; de Waal, F; Shafiq, K; Wotring, JW; Sexton, JZ; Weng, JK (American Chemical Society (ACS), 2022-01-04)

(3.6MB)

In silico analysis of SARS-CoV-2 proteins as targets for clinically available drugs.

Chan, WKB; Olson, KM; Wotring, JW; Sexton, JZ; Carlson, HA; Traynor, JR (Springer Nature, 2022-01-29)

(2.7MB)

Surface translocation of ACE2 and TMPRSS2 upon TLR4/7/8 activation is required for SARS-CoV-2 infection in circulating monocytes

Yao, Y; Subedi, K; Liu, T; Khalasawi, N; Pretto-Kernahan, CD; Wotring, JW; Wang, J; Yin, C; Jiang, A; Fu, C; Dimitrion, P; Li, J; Veenstra, J; Yi, Q; McKinnon, K; McKinnon, JE; Sexton, JZ; Zhou, L; Mi, QS (Springer Nature, 2022-12-01)

(3.7MB)

In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment

Wotring, JW; McCarty, SM; Shafiq, K; Zhang, CJ; Nguyen, T; Meyer, SR; Fursmidt, R; Mirabelli, C; Clasby, MC; Wobus, CE; O’Meara, MJ; Sexton, JZ (MDPI, 2022-08-01)

(2.5MB)

Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection

Qiao, Y; Wotring, JW; Zhang, CJ; Jiang, X; Xiao, L; Watt, A; Gattis, D; Scandalis, E; Freier, S; Zheng, Y; Pretto, CD; Ellison, SJ; Swayze, EE; Guo, S; Sexton, JZ; Chinnaiyan, AM (Public Library of Science (PLoS), 2023-02-01)

(2.3MB)

Painting and dissecting Epidermolysis Bullosa Simplex-associated keratin aggregates

Rietscher, K; Homberg, M; Kovalenko, I; Sexton, JZ; Rice, RH; Has, C; Omary, MB; Magin, TM (Elsevier, 2023-11-01)

(4.6MB)

High-Throughput Methods for the Discovery of Small Molecule Modulators of Pancreatic Beta-Cell Function and Regeneration

McCarty, SM; Clasby, MC; Sexton, JZ (Mary Ann Liebert, 2024-04-01)

(971.9KB)

A High-Throughput Microphysiological Liver Chip System to Model Drug-Induced Liver Injury Using Human Liver Organoids

Meyer, Sophia R; Zhang, Charles J; Garcia, Max A; Procario, Megan C; Yoo, Sanghee; Jolly, Amber L; Kim, Sumin; Kim, Jiho; Baek, Kyusuk; Kersten, Roland D; Fontana, Robert J; Sexton, Jonathan Z (Elsevier, 2024-08)

(2.3MB)

Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications

Sun, X; Huang, X; Park, KS; Zhou, X; Kennedy, AA; Pretto, CD; Wu, Q; Wan, Z; Xu, Y; Gong, W; Sexton, JZ; Tai, AW; Lei, YL; Moon, JJ (American Chemical Society (ACS), 2024-04-16)

(3.1MB)

Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response

Qiao, Yuanyuan; Chinnaiyan, Arul (Proceedings of the National Academy of Sciences, 2023-07-25)

(2.3MB)

Monoclonal Antibodies for Early Treatment of COVID-19 in a World of Evolving SARS-CoV-2 Mutations and Variants

Pogue, JM; Lauring, AS; Gandhi, TN; Marshall, VD; Eschenauer, GA; Nagel, JL; Baang, JH; Zhou, S; Valesano, AL; Petty, LA (Oxford University Press (OUP), 2021-07-01)

(168.8KB)

"Using a Multidisciplinary Team and Clinical Redesign to Improve Blood Pressure Control in Patients with Diabetes."

Choe, HM; Bernstein, SJ; Cooke, D; Stutz, D; Standiford, C (2007-04-01)

(82.8KB)

Bioaccumulation and Biodistribution Knowledgebase

Rosania, Gustavo R. (2011-06-13)