Now showing items 41-50 of 88
Design of a high-sensitivity classifier based on a genetic algorithm: application to computer-aided diagnosis
(IOP Publishing Ltd, 1998-10-01)
A genetic algorithm (GA) based feature selection method was developed for the design of high-sensitivity classifiers, which were tailored to yield high sensitivity with high specificity. The fitness function of the GA was ...
Testing of local gamma-ray scatter fractions determined by spectral fitting
(IOP Publishing Ltd, 1991-02-01)
The spectral-fitting method of correction for gamma-ray Compton scattering within objects separates the unscattered and scattered components of locally measured energy spectra. Here, the authors employ a third-order ...
Application of coded apertures in tomographic head scanning
(Elsevier, 1984-03-15)
A circular ring tomograph, designated SPRINT, is under development for single photon emission tomography of the human head. Most data to date have been gathered using a single rotating slit inside the detector ring to ...
Autoradiography-based, three-dimensional calculation of dose rate for murine, human-tumor xenografts
(Elsevier, 1993-11)
A Fast Fourier Transform method for calculating the three-dimensional dose rate distribution for murine, human-tumor xenografts is outlined. The required input includes evenly-spaced activity slices which span the tumor. ...
Proton and sodium MRI assessment of emerging tumor chemotherapeutic resistance
(John Wiley & Sons, Ltd., 2006-12)
The ultimate goal of any cancer therapy is to target the elimination of neoplastic cells. Although newer therapeutic strategies are in constant development, therapeutic assessment has been hampered by the inability to ...
Synthesis of a nonpeptide carbon-11 labeled substance P antagonist for PET studies
(Elsevier, 1993-05)
CP 96,345 is a nonpeptide high affinity antagonist of the substance P (NK1) receptor. The radiosynthesis of [11C]CP 96,345 suitable for Positron Emission Tomography (PET) applications is described. [11C]CP 96,345 was ...
Performance evaluation of a very high resolution small animal PET imager using silicon scatter detectors
(IOP Publishing Ltd, 2007-05-21)
A very high resolution positron emission tomography (PET) scanner for small animal imaging based on the idea of inserting a ring of high-granularity solid-state detectors into a conventional PET scanner is under investigation. ...
[omega]-iodophenyl fatty acids: A convenient method of radioiodination
(Elsevier, 1986)
A solid-phase radioiodination technique for [omega]-iodophenyl fatty acids using ammonium sulfate is described. The radioiodinations are (1) regioselective, (2) high in yield (95%), (3) short in reaction time (1 h) and (4) ...
A rapid high yield synthesis of no-carrier-added (-)-[123I]iodocyanopindolol
(Elsevier, 1991)
A convenient and efficient radiosynthesis of no-carrier-added [123I]labeled (-)iodocyanopindolol, (-)-[123I]ICYP, a high affinity [beta] adrenergic antagonist, is described. (-)-[123I]ICYP was synthesized by a modified ...